Logotype for Oculis Holding AG

Oculis Holding (OCS) investor relations material

Oculis Holding Status Update summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Logotype for Oculis Holding AG
Status Update summary6 Oct, 2025

Pipeline and Regulatory Progress

  • Achieved full FDA alignment to advance Privosegtor into registration trials for acute optic neuritis (AON) and non-arteritic anterior ischemic optic neuropathy (NAION), using a single IND for both indications.

  • PIONEER-1 (AON) to start in Q4 2025, PIONEER-2 (AON) in H1 2026, and PIONEER-3 (NAION) in mid-2026, all mirroring the successful phase II ACUITY trial design.

  • Privosegtor has received Orphan Drug designation from both FDA and EMA for AON.

  • Plans to cross-reference Privosegtor AON IND for a new IND submission in MS relapse in 2026.

  • OCS-01 for DME is in a phase III registration trial with readout expected in Q2 2026; company maintains a strong balance sheet with cash runway into end of 2027.

Clinical Trial Design and Endpoints

  • PIONEER-1 and -2 will use the same dose, patient population, and endpoints as ACUITY, focusing on LCVA change at month three as the primary endpoint.

  • Secondary endpoints include proportion of 15-letter gainers at three months and LCVA change at six months.

  • NAION trial (PIONEER-3) will leverage operational synergies with AON trials, using similar centers and data collection methods.

  • Each indication will have independent statistical powering to maximize success probability.

  • Privosegtor is a first-in-class neuroprotective peptoid targeting trophic factor pathways.

Market Opportunity and Unmet Need

  • AON and NAION are orphan indications with over 30,000 annual U.S. cases each and no approved therapies.

  • U.S. market potential estimated at over $3B for AON and $4B for NAION, with rare disease pricing analogs of $100k–$400k per treatment.

  • Both indications target concentrated prescriber bases and represent significant unmet needs in neuro-ophthalmology.

  • Privosegtor could become the first neuroprotective therapy to improve vision outcomes in these conditions.

  • ACUITY Phase 2 trial showed improvement in visual function and anatomical preservation of the retina.

Partial view of Summaries dataset, powered by Quartr API
Research faster. Power your platform.

Next Oculis Holding earnings date

Logotype for Oculis Holding AG
Q3 202510 Nov, 2025
Your earnings 
season toolkit.
Download
Free on both iOS & Android.

Next Oculis Holding earnings date

Logotype for Oculis Holding AG
Q3 202510 Nov, 2025

The essential earnings season companion

The #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.

Live calls and transcripts

Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.

Find what you need faster

Search for any keyword across all transcripts simultaneously.

Easily store key findings

Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.

Your watchlist. Your dashboard.

Follow the companies that matter to you. Get a personalized feed with real-time updates.

Be the first to know

Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.

Consensus estimates

Access analyst consensus estimates, valuation multiples, and revenue segments splits.

All IR material in one place

The easiest way to stay updated during earnings season.

Global coverage

All events from public companies. Live and recorded.

Just click and listen

No webcast links. No manual registrations.

Research anytime, anywhere

Built for professionals. Loved by everyone. Try our free mobile app.

excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
App-store-avatar.png play-store-avatar.png
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
play-store-avatar
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
App-store-avatar.png play-store-avatar.png
anuj283App Store
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
App-store-avatar.png play-store-avatar.png
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
play-store-avatar
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
App-store-avatar.png play-store-avatar.png
anuj283App Store
I can't remember the last time an app had such a positive impact on my investment process.
x-avatar
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
App-store-avatar.png play-store-avatar.png
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
x-avatar
@theshortbearx.com
I can't remember the last time an app had such a positive impact on my investment process.
x-avatar
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
App-store-avatar.png play-store-avatar.png
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
x-avatar
@theshortbearx.com

Frequently asked questions

Oculis Holding AG is a global biopharmaceutical company focused on developing innovative treatments for eye diseases. The company's product pipeline includes several advanced-stage candidates designed to address significant unmet needs in ophthalmology. Notable among these are OCS-01, a topical eye drop for diabetic macular edema and post-cataract surgery inflammation, OCS-02, a topical biologic targeting dry eye disease and uveitis, and OCS-05, aimed at neuro-ophthalmic conditions such as acute optic neuritis and glaucoma. The company is headquartered in Zug, Switzerland, and its shares are listed on the Nasdaq.

Quartr provides global coverage of all investor relation material from public companies.

  • Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.

  • Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.

  • Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.

Yes, the Quartr mobile app is free on both iOS and Android.

Yes. Quartr provides global, industry-leading live coverage of company events such as regular earnings calls, capital markets days, M&A announcements, and investor conferences. Live with zero delays. Just click and listen.

Yes, capturing important takeaways is as simple as it gets. Even during your lunch run or commute.

Yes. Follow the companies that matter to you. Get a personalized feed with real-time updates, a tailored earnings calendar, and instant alerts when earnings calls go live.

Yes. Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned, regardless of who's talking.

Explore our global coverage