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OmniAb (OABI) investor relations material

OmniAb Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary4 Nov, 2025

Executive summary

  • Achieved record-high 104 active partners and 399 active programs by end of Q3 2025, reflecting strong growth and diversification through new license agreements and program additions.

  • Launched and expanded technology initiatives, including the xPloration Partner Access Program and the upcoming OmniUltra platform, expected to broaden market opportunities and drive partner engagement.

  • Strengthened balance sheet with a $30 million private placement in August 2025, welcoming new shareholders and enhancing financial flexibility.

  • Realigned staffing and reduced operating expenses to enhance efficiency and operational execution.

  • Revenue is primarily from license fees, milestones, and service revenue, with long-term value expected from royalties on partner product sales.

Financial highlights

  • Q3 2025 revenue was $2.2 million, down from $4.2 million in Q3 2024, mainly due to lower milestone and service revenue; nine-month 2025 revenue was $10.3 million, down from $15.6 million in 2024.

  • Net loss for Q3 2025 was $16.5 million ($0.14/share), compared to $16.4 million ($0.16/share) in Q3 2024; nine-month net loss was $50.6 million ($0.46/share) versus $49.0 million ($0.48/share) in 2024.

  • Operating expenses for Q3 2025 were $20.4 million, down from $23.9 million year-over-year; nine-month operating expenses were $63.5 million, down 14%.

  • Ended Q3 2025 with $59.5 million in cash, cash equivalents, and short-term investments.

  • Net cash used in operating activities for the nine months ended September 30, 2025 was $30.8 million.

Outlook and guidance

  • 2025 revenue guidance updated to $18–22 million; operating expenses expected at $82–86 million.

  • Year-end 2025 cash balance projected at $52–56 million, with cash use lower than 2024 (excluding financings).

  • Some anticipated milestones shifted to 2026 due to partner timing.

  • Management believes existing cash and investments are sufficient to support operations for at least 12 months from the report date.

  • Full-year 2025 effective tax rate anticipated to be approximately 0%.

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Frequently asked questions

OmniAb Inc. is a biotechnology firm specializing in the discovery and development of therapeutic antibodies. The company operates a unique discovery platform that leverages the biological intelligence of proprietary transgenic animals, including OmniRat, OmniChicken, and OmniMouse, which are engineered to produce antibodies with human sequences. This approach facilitates the development of human therapeutic candidates. The company is headquartered in Emeryville, California, and its shares are listed on the Nasdaq.

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