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OmniAb (OABI) investor relations material
OmniAb Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary4 Nov, 2025
Executive summary
Achieved record-high active partner base of 104 and 399 active programs as of September 30, 2025, with strong year-over-year growth and new license agreements with A*Star, University of Leeds, and Dana-Farber Cancer Institute.
Previewed and scheduled December launch of OmniUltra, a novel transgenic chicken platform for antibody and peptide discovery, expected to open new markets and business opportunities.
Realigned staffing and reduced operating expenses to drive efficiencies in a scalable operating model.
Strengthened balance sheet with a $30 million private placement in August 2025, welcoming new shareholders and enhancing financial flexibility.
Continued execution on strategic initiatives, technology platform expansion, and published research with GSK on Nav1.1 sodium channel potentiator.
Financial highlights
Q3 2025 revenue was $2.2 million, down from $4.2 million in Q3 2024, mainly due to lower milestone and service revenue; nine-month revenue was $10.3 million, down 34%.
Net loss for Q3 2025 was $16.5 million ($0.14 per share), compared to $16.4 million ($0.16 per share) in Q3 2024; nine-month net loss was $50.6 million ($0.46 per share).
Operating expenses for Q3 2025 were $20.4 million, down from $23.9 million year-over-year; nine-month operating expenses were $63.5 million, down 14%.
Ended Q3 2025 with $59.5 million in cash, cash equivalents, and short-term investments.
Service revenue decreased due to completion of a small-molecule ion channel program; royalty revenue remained stable.
Outlook and guidance
2025 revenue guidance is $18–22 million; operating expenses expected at $82–86 million.
Year-end 2025 cash projected between $52–56 million; cash use in 2025 expected to be lower than 2024, excluding financings.
Full-year 2025 effective tax rate anticipated to be approximately 0%.
Some anticipated milestones shifted to 2026 due to partner timing.
Management believes existing cash and investments are sufficient to support operations for at least 12 months from the report date.
xPloration sales funnel conversion timeline
OmniUltra's near-term revenue generation potential
Drivers for 2025 guidance revision
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Frequently asked questions
OmniAb Inc. is a biotechnology firm specializing in the discovery and development of therapeutic antibodies. The company operates a unique discovery platform that leverages the biological intelligence of proprietary transgenic animals, including OmniRat, OmniChicken, and OmniMouse, which are engineered to produce antibodies with human sequences. This approach facilitates the development of human therapeutic candidates. The company is headquartered in Emeryville, California, and its shares are listed on the Nasdaq.
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