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Investor Relations14 Oct 2025
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Oncolytics Biotech (ONCY) investor relations material
Oncolytics Biotech Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary8 Aug, 2025
Executive summary
Transitioning from proof-of-concept to regulatory clarity for pelareorep, focusing on registration-enabling studies in first-line metastatic pancreatic ductal adenocarcinoma (mPDAC).
New CEO and Chief Business Officer appointed, both with significant biotech transaction experience.
Pelareorep shows ability to convert immunologically "cold" tumors to "hot," enhancing immune response and survival in mPDAC and breast cancer.
Strategic prioritization of mPDAC program based on compelling survival and translational data, with regulatory discussions underway.
Financial highlights
Cash and cash equivalents of $14.6 million as of June 30, 2025, with projected runway into Q1 2026.
Net loss for Q2 2025 was $6.2 million, improved from $7.3 million in Q2 2024; loss per share was $0.07 vs. $0.10 year-over-year.
R&D expenses for Q2 2025 were $2.8 million, down from $4.6 million in Q2 2024, reflecting focus on GOBLET study.
General and administrative expenses decreased to $2.9 million from $3.4 million year-over-year.
Net cash used in operating activities for the first half of 2025 was $12.0 million, down from $14.3 million in the same period of 2024.
Outlook and guidance
Updated clinical timeline for registration-enabling pivotal study in 1L mPDAC expected in Q3 2025.
Start-up activities for pivotal study anticipated as early as Q4 2025, pending regulatory feedback.
Updated safety and efficacy data for GOBLET study Cohort 4 in anal carcinoma expected by end of 2025.
Initial responses from the U.S. PTO on patent extension for pelareorep expected in Q4 2025.
Which treatment regimens for mPDAC pivotal study?
What is pelareorep's competitive edge in 1L mPDAC?
Funding strategy for mPDAC pivotal study beyond Q1 2026?
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Next Oncolytics Biotech earnings date
Q3 202511 Nov, 2025
Next Oncolytics Biotech earnings date
Q3 202511 Nov, 2025
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Frequently asked questions
Oncolytics Biotech Inc is a biotechnology company developing immuno-oncology therapies to treat various cancers. The company focuses on the development of proprietary viral-based therapies that stimulate the immune system to target and destroy cancer cells. Oncolytics Biotech conducts clinical research and collaborates with pharmaceutical and academic partners. The company is headquartered in Calgary, Canada, and its shares are listed on the NASDAQ.
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