Oncopeptides
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Oncopeptides (ONCO) investor relations material

Oncopeptides Trading update summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Trading update summary16 Jan, 2026

Financial performance and guidance

  • Q4 2025 net sales reached SEK 18.6 million, up 88% year-over-year and 125% versus 2024, with full-year 2025 sales totaling 71.2 million SEK.

  • Full-year sales of Pepaxti more than doubled in 2025, led by strong growth in Italy, but offset by slower uptake in Germany and a doctors' strike in Spain.

  • Sales in Spain were negatively impacted by a nationwide doctor strike, leading to results below projections and a shift in profitability expectations to 2027.

  • Cost optimization and strategic reviews are underway, especially in Germany, to align costs with revenue and support profitability at the country level in 2026.

  • Positive cash flow is now expected in 2027, later than previously anticipated.

Market dynamics and regional performance

  • Italy exceeded expectations with 90% regional access and strong demand, validating the clinical experience strategy.

  • Germany's growth was steady but limited by restricted access to healthcare professionals and increased competition, prompting a strategic focus on high-potential regions.

  • Spain achieved 100% access but suffered a significant sales decline due to a high-participation doctor strike and seasonal factors.

  • Greece showed positive momentum but experienced quarterly fluctuations due to centralized ordering and budget constraints.

  • Commercialization phases completed in several European countries, with approximately 55% of market potential reached and market exclusivity in Europe secured until 2037.

Expansion and partnership strategy

  • Active partnership discussions are ongoing for Central and Eastern Europe, with advanced talks and a non-binding licensing offer received in Japan.

  • Japan is seen as a promising market with centralized prescribers and a regulatory pathway similar to Italy's dynamics.

  • Global expansion includes licensing deals in South Korea and opportunistic partnerships in the MENA region, expected to contribute to 2026 revenues.

  • Nordic expansion is challenged by small market size and complex reimbursement processes, with ongoing efforts in Norway, Sweden, and Finland.

  • Partnerships are being pursued for market access and regulatory processes in various regions.

Impact of cash flow delay on operations
How will Germany achieve country-level profitability?
Timeline for Japan licensing deal finalization?
Impact of Spain strike on 2027 cash flow target?
Germany: How will focus areas drive 2026 profitability?
Japan partnership: What are the final hurdles?
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Frequently asked questions

Oncopeptides AB, a biotech company, focuses on the development of therapies for patients with cancer. The company's lead drug candidate is melflufen, which has received orphan drug designation from the European Commission, as well as from the FDA for the treatment of multiple myeloma. Its product pipeline also comprises peptide-drug conjugates that are in preclinical stage development for hematological malignancies and solid tumors. The company is based in Stockholm, Sweden

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