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Oncopeptides (ONCO) investor relations material

Oncopeptides CMD 2025 summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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CMD 2025 summary13 Nov, 2025

Current business performance and market position

  • Achieved SEK 20 million in Q3 2025 sales, marking 174% year-over-year growth and four consecutive quarters of European commercialization growth.

  • Pepaxti is now available in key European markets (Germany, Austria, Spain, Italy), with profitability targeted by end of 2026.

  • Over 550 patients treated across Europe, with positive clinical experience and inclusion in European guidelines.

  • Strategic partnerships are expanding access to new geographies, including South Korea, MENA, and ongoing late-stage due diligence for Japan.

  • Real-world data and clinical endorsements are driving broader adoption and market confidence.

Product innovation and clinical differentiation

  • Pepaxti (melflufen) is the first peptide drug conjugate from the platform, offering a unique, immune-independent mechanism of action.

  • Demonstrates efficacy in triple-class refractory multiple myeloma, including high-risk and elderly patients, and is suitable as bridging therapy before immunotherapies.

  • Once-monthly IV administration supports patient quality of life and logistical flexibility.

  • Safety profile is favorable, with manageable hematologic toxicity and minimal non-hematologic side effects.

  • Real-world and clinical trial data confirm durable benefit, manageable toxicity, and broad applicability across patient subgroups.

Strategic pipeline and future growth opportunities

  • Pipeline includes next-generation PDCs (OPD5, OPDC3) and the SPiKEs platform for NK cell engagement, targeting oncology, hematology, and autoimmune diseases.

  • OPD5 shows promise in combination regimens and glioblastoma, with strong preclinical data and blood-brain barrier penetration.

  • SPiKEs platform offers differentiated, tolerable immunotherapy options for both cancer and autoimmune indications, with unique BCMA targeting.

  • Preclinical progress is advancing assets toward IND readiness, with a focus on scalable manufacturing and strategic partnerships for clinical development.

  • The company is leveraging grants, collaborations, and licensing deals to support pipeline advancement and global expansion.

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Q4 202519 Feb, 2026
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Frequently asked questions

Oncopeptides AB, a biotech company, focuses on the development of therapies for patients with cancer. The company's lead drug candidate is melflufen, which has received orphan drug designation from the European Commission, as well as from the FDA for the treatment of multiple myeloma. Its product pipeline also comprises peptide-drug conjugates that are in preclinical stage development for hematological malignancies and solid tumors. The company is based in Stockholm, Sweden

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