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OptiNose (OPTN) investor relations material
OptiNose Q4 2024 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
XHANCE net revenue reached $22.4 million in Q4 2024 and $78.2 million for the full year, up 13% and 10% year-over-year, respectively.
Prescription demand inflected upward in September 2024, with Q4 NRx up 12% and TRX up 23% sequentially from Q3 2024.
Achieved first-ever positive income from operations in Q4 2024 at $0.4 million.
Financial highlights
Q4 2024 net revenue: $22.4 million (up 13% year-over-year); full year 2024: $78.2 million (up 10%).
Q4 2024 net loss: $0.4 million ($0.04/share); full year 2024 net loss: $21.5 million ($2.12/share), both improved from prior year.
Cash and cash equivalents at year-end: $84.5 million.
SG&A plus R&D expenses for 2024: $87.3 million, up from $85.1 million in 2023.
Weighted average shares outstanding for 2024: 10.2 million.
Segment performance
XHANCE prescriptions showed strong growth: NRx up 12% and TRX up 23% sequentially from Q3 to Q4 2024.
- FDA approval and expanded access drive higher revenue and improved 2025 profitability outlook.OPTN
Q2 20242 Feb 2026 - FDA approval and expanded launch position XHANCE for major growth in chronic sinusitis treatment.OPTN
H.C. Wainwright 26th Annual Global Investment Conference21 Jan 2026 - Q3 revenue up 3% to $20.4M, but 2024 guidance cut and going concern risk remains.OPTN
Q3 202415 Jan 2026 - Label expansion for XHANCE unlocks a large market, driving growth and strategic opportunities.OPTN
Piper Sandler 36th Annual Healthcare Conference11 Jan 2026
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