)
Visual24 Oct 2025
The rise of Alphabet
Oruka Therapeutics (ORKA) investor relations material
Oruka Therapeutics Study Presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Study Presentation summary18 Sep, 2025
Mechanism of action and molecular design
ORKA-001 is a humanized IgG1 monoclonal antibody targeting the p19 subunit of IL-23, inhibiting its receptor interaction.
Engineered Fc region ablates effector function and extends half-life via YTE substitutions, increasing FcRn binding and recycling.
Demonstrates similar epitope binding and potency to risankizumab in multiple assays.
Phase 1 trial design and participant characteristics
Double-blind, placebo-controlled, single ascending dose study in healthy adults, with 3 dose cohorts (300, 600, 1200 mg SC).
Primary endpoints: safety and tolerability; secondary: pharmacokinetics; exploratory: pharmacodynamics.
Baseline demographics were typical for healthy volunteers, with balanced age, sex, and BMI across cohorts.
Safety and tolerability
Safety profile consistent with IL-23p19 inhibitors; no serious adverse events or discontinuations due to adverse events.
Most common adverse events were headache, upper respiratory tract infection, and transient injection site erythema.
What Ctrough level is needed for efficacy?
How will EVERLAST-A validate annual dosing?
What supports off-treatment remission potential?
Partial view of Summaries dataset, powered by Quartr API
Research faster. Power your platform.
Next Oruka Therapeutics earnings date
Q3 202512 Nov, 2025
Next Oruka Therapeutics earnings date
Q3 202512 Nov, 2025
The essential earnings season companion
The #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Live calls and transcripts
Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.
Find what you need faster
Search for any keyword across all transcripts simultaneously.
Easily store key findings
Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Your watchlist. Your dashboard.
Follow the companies that matter to you. Get a personalized feed with real-time updates.
Be the first to know
Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.
Consensus estimates
Access analyst consensus estimates, valuation multiples, and revenue segments splits.
All IR material in one place
The easiest way to stay updated during earnings season.
Global coverage
All events from public companies. Live and recorded.
Just click and listen
No webcast links. No manual registrations.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
)
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
)
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
anuj283App Store
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
anuj283App Store
I can't remember the last time an app had such a positive impact on my investment process.
)
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
@theshortbearx.com
I can't remember the last time an app had such a positive impact on my investment process.
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
@theshortbearx.com
)
)
Frequently asked questions
Oruka Therapeutics Inc. is a biopharmaceutical company focused on developing innovative treatments for various medical conditions. The company specializes in research and development activities, aiming to address unmet medical needs through advanced therapeutic solutions. Oruka Therapeutics operates within the healthcare sector, leveraging cutting-edge technologies to create potential treatments for patients worldwide. The company is headquartered in Westminster, Colorado, and its shares are listed on the Nasdaq.
Quartr provides global coverage of all investor relation material from public companies.
Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.
Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.
Yes, the Quartr mobile app is free on both iOS and Android.
Yes. Quartr provides global, industry-leading live coverage of company events such as regular earnings calls, capital markets days, M&A announcements, and investor conferences. Live with zero delays. Just click and listen.
Yes, capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Yes. Follow the companies that matter to you. Get a personalized feed with real-time updates, a tailored earnings calendar, and instant alerts when earnings calls go live.
Yes. Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned, regardless of who's talking.
Explore our global coverage