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Oxford Nanopore Technologies (ONT) investor relations material
Oxford Nanopore Technologies H1 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H1 2025 earnings summary2 Sep, 2025
Executive summary
Achieved H1 2025 revenue of £105.6 million, up 28% constant currency and 25.6% reported, surpassing expectations and outpacing end markets.
Broad-based growth across all geographies, end markets, and product types, with APAC and EMEAI leading regional performance.
Significant progress on path to profitability, with adjusted EBITDA loss improving 22% year-on-year to £48.3 million.
Strategic focus on high-priority market segments and continued innovation underpin sustained, above-market growth.
CEO announced intention to step down at end of 2026 after 21 years.
Financial highlights
Gross margin at 58.2%, just below 59% target, impacted by a £3.3 million one-off inventory charge; excluding this, gross margin would have been 61%.
Cash, cash equivalents, and liquid investments stood at £337.3 million as of 30 June 2025.
Adjusted EBITDA loss improved to £48.3 million from £61.7 million in H1 2024.
Net cash outflow from operating activities was £48.4 million, improved from £59.9 million in H1 2024.
Operating expenses up just 1% year-on-year, reflecting strong cost control.
Outlook and guidance
FY25 guidance reaffirmed: revenue growth of 20–23% constant currency, gross margin around 59%, and adjusted OPEX growth of 3–4%.
On track for adjusted EBITDA breakeven in 2027 and cash flow breakeven in 2028.
H2 revenue growth expected to be lower than H1 due to strong prior-year comparatives.
Medium-term targets unchanged: >30% revenue CAGR (FY24–FY27), gross margin above 62% by FY27.
Pricing model changes and operational improvements expected to continue benefiting margins and cash flow.
Key drivers for >62% gross margin by 2027?
Strategy for 2026-27 growth acceleration
Expected 2026 device volume trend post pricing model?
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Next Oxford Nanopore Technologies earnings date
Investor Update14 Nov, 2025
Next Oxford Nanopore Technologies earnings date
Investor Update14 Nov, 2025
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Oxford Nanopore Technologies plc develops and commercializes sequencing platforms for analyzing DNA and RNA. Its devices use nanopore-based technology to deliver real-time, scalable data for research and clinical applications. The company serves academic, clinical, and industrial users worldwide. The company is headquartered in Oxford, United Kingdom, and its shares are listed on the London Stock Exchange.
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