)
Passage Bio (PASG) investor relations material
Passage Bio Chardan’s 9th Annual Genetic Medicines Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Program overviews and recent milestones
Companies focus on gene therapies for neurodegenerative diseases, emphasizing local delivery and in-house manufacturing to improve safety and reduce costs.
Recent milestones include positive phase II data in Parkinson's, Huntington's, and frontotemporal dementia, with several programs approaching BLA filings.
AI partnerships are being leveraged to analyze clinical data and enhance endpoint robustness, particularly in Parkinson's studies.
Durable biomarker engagement and stabilization of neurodegeneration markers have been demonstrated in clinical trials.
Preclinical programs are advancing, targeting novel pathways such as DNA damage response in Huntington's disease.
Key challenges in gene therapy for neurodegenerative diseases
Delivery to the correct brain regions remains a primary challenge, with local administration favored for precision and safety.
Slow disease progression complicates clinical trial design and endpoint measurement, making it difficult to demonstrate efficacy.
Heterogeneity among patients requires advanced statistical and AI methods to distinguish true treatment effects from noise.
Regulatory agencies are increasingly open to novel endpoints and trial designs, especially for rare diseases with high unmet need.
Safety concerns persist, but local delivery and lower vector doses have shown improved safety profiles compared to systemic approaches.
Regulatory and access considerations
FDA is showing flexibility for rare, high-unmet-need diseases, allowing single-arm studies with supportive evidence.
Use of natural history data and external controls is gaining acceptance to address patient heterogeneity.
AI-driven analysis is being used to enhance endpoint robustness and reduce bias in imaging and clinical data.
Access challenges include the need for specialized centers and trained surgeons, but procedures are being designed to fit existing hospital workflows.
Strong clinical data is expected to drive rapid adoption despite procedural complexities.
Next Passage Bio earnings date
Next Passage Bio earnings date
The essential earnings season companion
The #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Live calls and transcripts
Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.
Find what you need faster
Search for any keyword across all transcripts simultaneously.
Easily store key findings
Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Your watchlist. Your dashboard.
Follow the companies that matter to you. Get a personalized feed with real-time updates.
Be the first to know
Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.
Consensus estimates
Access analyst consensus estimates, valuation multiples, and revenue segments splits.
All IR material in one place
The easiest way to stay updated during earnings season.
Global coverage
All events from public companies. Live and recorded.
Just click and listen
No webcast links. No manual registrations.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
I can't remember the last time an app had such a positive impact on my investment process.
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
I can't remember the last time an app had such a positive impact on my investment process.
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
Frequently asked questions
Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.
Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.
Explore our global coverage
)
)