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Penumbra (PEN) investor relations material

Penumbra Morgan Stanley 23rd Annual Global Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Morgan Stanley 23rd Annual Global Healthcare Conference summary9 Sep, 2025

Leadership and organizational updates

  • Recent transition in leadership with Shruthi Narayan becoming President, reflecting a natural progression after significant contributions to business growth and innovation.

  • Expansion of specialized teams to focus on embolization and CAVT opportunities, ensuring dedicated attention to each product line.

  • Communication and morale were managed effectively during organizational changes, maintaining stability and excitement among staff.

  • Sales leadership structure remains unified, supporting cross-pollination and focus across divisions.

Clinical trials and innovation

  • The STORM-PE trial is the first randomized controlled trial comparing mechanical thrombectomy to anticoagulation in intermediate and high-risk PE patients, aiming to provide level one evidence for clinical management.

  • Positive trial results could shift treatment paradigms, leading to more patients being referred for advanced intervention rather than anticoagulation.

  • The trial's primary endpoint focuses on rapid right heart recovery, with secondary endpoints assessing quality of life and functional outcomes.

  • Data dissemination will target both interventional and non-interventional communities, with guideline updates expected over time.

Product development and market strategy

  • Thunderbolt, a new stroke product, aims to improve clot ingestion times and is anticipated to drive further innovation and pricing flexibility.

  • Pricing strategies are designed to ensure hospital profitability and facilitate adoption, with Thunderbolt positioned to be cost-effective compared to current alternatives.

  • Ruby XL expands the embolization coil portfolio to larger catheter profiles, addressing a previously underserved 20% of the market and receiving positive early feedback.

  • Dedicated teams for embolization and CAVT are expected to accelerate share gains and innovation.

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Frequently asked questions

Penumbra Inc designs, develops, and markets medical devices for neurovascular and vascular conditions. Its products support treatments for stroke, peripheral embolization, and thrombectomy procedures, serving healthcare providers and hospitals worldwide. Penumbra operates within the healthcare and medical device sectors. The company is headquartered in Alameda, California, and its shares are listed on the NYSE.

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