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PeptiDream (4587) investor relations material

PeptiDream Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary8 Aug, 2025

Executive summary

  • Q2 FY2025 revenue was ¥8.54B, down 76.4% year-over-year, with a net loss of ¥2.12B; full-year guidance remains at ¥49B revenue and ¥15.1B net income.

  • Drug Discovery segment saw a sharp revenue decline and loss, while Radiopharmaceuticals grew revenue and returned to profitability.

  • Radiopharmaceuticals and non-radiopharmaceuticals advanced pipelines, with new clinical milestones and expanded partnerships.

  • Special Investigation Committee found inappropriate reagent removal and unauthorized contracts by a former executive, but no significant financial impact is expected.

  • Cash and cash equivalents decreased by ¥14.79B to ¥33.33B, mainly due to operating losses and tax payments.

Financial highlights

  • Q2 FY2025 revenue: ¥8.54B; EBITDA: -¥1.61B; core operating profit: -¥2.61B; net income: -¥2.12B.

  • Core operating loss was ¥2.61B, versus a core operating profit of ¥24.77B a year earlier.

  • Basic and diluted EPS were both (¥16.40), compared to ¥138.30 and ¥138.11 in the previous year.

  • Total assets fell to ¥78.54B from ¥92.77B at year-end 2024.

  • 1H FY2025 cash and equivalents fell by ¥10.9B, mainly due to net loss and tax payments.

Outlook and guidance

  • Full-year FY2025 guidance unchanged; revenue forecast at ¥49B, net income at ¥15.1B, and core operating profit at ¥21.7B.

  • R&D expenses for 2025 projected at ¥5.65B, with capital expenditures of ¥5.05B.

  • Focus on closing ongoing negotiations and new deals for FY2026.

  • Anticipates increased milestone payments and greater contribution from non-radiopharmaceuticals.

  • No revisions to the previously announced financial forecast.

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Frequently asked questions

PeptiDream Inc. is a Japan-based biotechnology company specializing in peptide-based drug discovery and development. The company utilizes its proprietary Peptide Discovery Platform System (PDPS) to identify and optimize peptide therapeutics for various medical applications. PeptiDream collaborates with global pharmaceutical companies to develop novel therapeutics across multiple disease areas. Its research and development efforts focus on peptide-drug conjugates, small-molecule drugs, and peptide-based imaging agents. The company is headquartered in Kawasaki, Japan, and its shares are listed on the TSE.

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