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Philogen (PHIL) investor relations material
Philogen Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary26 Sep, 2025
Executive summary
Announced major licensing agreements with RayzeBio (BMS) and Racebio for OncoACP3/OncoCP3, each with $350 million upfront and up to $1 billion in milestones and royalties, significantly strengthening financial resources.
Focused on advancing late-stage clinical programs, especially Nidlegy and Fibromun, and expanding the pipeline with new trials and molecules, supported by a vertically integrated R&D and manufacturing model.
Revenues from contracts with customers rose to €5.5 million, with total revenues reaching €8.7 million, up €7 million year-over-year, driven by clinical trial progress and product sales.
Expanded operations with new clinical offices in Milan, facility upgrades in Monteriggioni and Zurich, and increased research and clinical teams.
Voluntary withdrawal of Nidlegy EMA application to collect additional CMC and clinical data, with resubmission planned.
Financial highlights
Cash and cash equivalents at the end of H1 2025 were €100 million, with liquidity exceeding €350 million after major licensing inflows.
Total revenues for H1 2025: €8.7 million, up €7 million year-over-year, driven by contract manufacturing, licensing, and product sales.
EBITDA: -€13.9 million (improved from -€15.2 million in H1 2024); EBIT: -€15.8 million; net loss: €14.9 million (vs. €15.5 million in H1 2024).
Net financial position: €88.5 million surplus, with €100 million in cash and €88.8 million in liquid financial assets.
Operating costs increased 33% year-over-year, mainly due to higher R&D, clinical trial, and personnel expenses.
Outlook and guidance
Plans to invest new resources in late-stage products and launch additional global trials in non-melanoma skin cancers.
Regulatory resubmission for Nidlegy planned for mid-2026, with ongoing dialogue with authorities and US Phase III two-thirds enrolled.
Anticipates communicating first-line soft tissue sarcoma trial results and progressing glioblastoma trials in coming months.
Multiple Phase I clinical trials for new drug candidates planned over the next 24 months.
Continued collaborations with Sun Pharma, Pfizer, Janssen, Bracco, MSD, and RayzeBio.
RayzeBio payment: future R&D priorities?
Nidlegy™ EU/US regulatory strategy?
OncoCAIX direct Phase III rationale?
ONCOC9: What is the Phase III launch timeline?
Nidlegy EMA resubmission: Next key steps?
Nidlegy US market strategy post-RayzeBio deal?
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Q3 202511 Nov, 2025
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Frequently asked questions
Philogen S.p.A. is an Italy-based biotechnology company focused on the research and development of targeted therapies for cancer and other serious diseases. The company specializes in antibody-based and small-molecule therapeutics, leveraging its expertise in tumor-targeting technologies. Philogen develops biologic drugs designed to deliver therapeutic agents directly to diseased tissues while minimizing effects on healthy cells. Its research spans from early discovery to clinical development, with a focus on immunotherapy and vascular targeting. The company is headquartered in Siena, Italy, and its shares are listed on the Borsa Italiana.
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