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Plus Therapeutics (PSTV) investor relations material
Plus Therapeutics Business update summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Financial Update and Capital Position
Completed an oversubscribed $15 million offering, extending runway through 2027 and enabling growth initiatives.
Access to three ongoing grants supports clinical milestones and operations through 2027.
Current cash and grants are expected to fund all planned milestones, with CNSIDE business targeting break-even by 2027, though clinical programs will continue to use cash.
No immediate plans for a reverse stock split; focus remains on execution and generating positive catalysts.
Market Opportunity and Unmet Needs
Over 1 million U.S. patients are at risk of CNS metastases, with up to 30% of adult cancer patients developing CNS mets, representing a significant and growing market.
CNSide diagnostic platform targets a $6B U.S. market, with a projected 500,000 patients per year and a commercial relaunch planned for Q3 2025.
REYOBIQ radiotherapeutic addresses a $16B U.S. market, offering up to 20x radiation delivery versus standard of care and benefiting from FDA Fast Track and Orphan Designations.
Diagnostic and Therapeutic Innovation
CNSide offers a comprehensive, highly sensitive tumor cell capture and interrogation system, with 95% specificity and 92% sensitivity, and over 11,000 tests completed.
The platform provides four tests from a single sample, enabling diagnosis, treatment monitoring, and personalized therapy selection.
REYOBIQ is a first-in-class targeted radiotherapeutic with dual delivery modalities, capable of delivering up to 20x the radiation dose of standard care directly to CNS tumors.
CNSide Diagnostics offers proprietary CSF assays to improve management of leptomeningeal metastases.
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