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Edge12 Dec 2025
Running on Clouds: The Story of On
The story of how a Swiss runner's pursuit of a new running sensation became On, aiming to be the most premium global sportswear brand worldwide.
Poxel (POXEL) investor relations material
Poxel Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary10 Dec, 2025
Executive summary
Revenue nearly doubled year-over-year in H1 2025, while net loss was significantly reduced to €2.6 million from €7.3 million in H1 2024.
Receivership proceedings commenced in August 2025, with a six-month observation period and a finalized recovery plan pending court approval.
Change in governance with new board members and CEO appointments during the observation period.
Financial highlights
Revenue for H1 2025 was €2.18 million, up 88% from €1.16 million in H1 2024, mainly from royalties on TWYMEEGⓇ sales in Japan.
Gross margin improved to €306 thousand from €16 thousand year-over-year.
Net loss narrowed to €2.62 million from €7.26 million in H1 2024.
General and administrative expenses were reduced to €1.76 million from €3.21 million, reflecting cost-saving measures.
Financial loss decreased to €653 thousand from €3.55 million, aided by foreign exchange gains.
Outlook and guidance
Recovery plan finalized and awaiting court decision, with the aim to secure new partnerships and monetize assets.
TWYMEEGⓇ sales in Japan expected to reach ¥11.2 billion for FY 2025, a 47% increase year-over-year.
Double-digit royalty growth and additional milestone payments anticipated beyond 2025.
Post-Feb 2026 financing strategy
Impact of OrbiMed debt on TWYMEEG® cash flow
AGM's role in recovery plan implementation
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Q4 202523 Mar, 2026
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Frequently asked questions
Poxel S.A. is a clinical-stage biopharmaceutical company focused on developing innovative treatments for serious chronic diseases, particularly those related to metabolic disorders. The company's research pipeline includes treatments for conditions like non-alcoholic steatohepatitis (NASH) and rare metabolic diseases such as adrenoleukodystrophy (ALD). Poxel leverages proprietary platforms including adenosine monophosphate-activated protein kinase (AMPK) activators and deuterated thiazolidinedione (TZD) compounds. The company is headquartered in Lyon, France, with additional offices in Boston, Massachusetts, and Tokyo, Japan. Its shares are listed on Euronext Paris.
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