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Rafael (RFL) investor relations material
Rafael Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary29 Oct, 2025
Executive summary
Advanced pivotal Phase 3 TransportNPC™ trial for Trappsol® Cyclo™ in Niemann-Pick Disease Type C1, with continued enrollment following positive DMC review.
Strengthened leadership with appointment of new COO, board member, and audit committee chair.
Closed a $25 million rights offering in June 2025, enhancing liquidity for ongoing and future programs.
Financial highlights
Cash and cash equivalents stood at $52.8 million as of July 31, 2025.
Net loss for Q4 2025 was $12.1 million ($0.28/share), up from $4.5 million ($0.19/share) year-over-year, mainly due to consolidation of Cyclo and other entities.
Full-year net loss was $30.5 million ($1.04/share), an improvement from $34.4 million ($1.45/share) in the prior year.
Research and development expenses rose to $7.5 million in Q4 and $12.8 million for the year, reflecting new acquisitions.
General and administrative expenses increased to $5.5 million in Q4 and $13.8 million for the year.
Outlook and guidance
Management remains optimistic about advancing Trappsol® Cyclo™ and investing in additional opportunities, supported by improved financial position.
Significance of DMC's trial continuation?
Jonas family's backstop commitment signal?
What drove the FY25 net loss decrease?
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Frequently asked questions
Rafael Holdings Inc operates as a holding company with interests in pharmaceutical development and commercial real estate. The company’s healthcare focus involves supporting novel therapeutics, while its real estate operations include ownership and management of commercial properties. Rafael Holdings serves the healthcare and real estate sectors. The company is headquartered in Newark, New Jersey, and its shares are listed on the NYSE American.
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