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Relmada Therapeutics (RLMD) investor relations material

Relmada Therapeutics Small-Cap Virtual Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Small-Cap Virtual Conference summary18 Sep, 2025

Strategic updates and program focus

  • Shifted to lower-risk programs, acquiring two new assets this year to drive near-term value.

  • NDB-01, an extended-release intravesical chemotherapy gel for non-muscle invasive bladder cancer, is the most advanced asset and main value driver for the next 1-2 years.

  • Sopranolol, a subcutaneous injection for compulsive disorders, is being advanced for Prader-Willi syndrome with phase 2 planned for late H1 next year.

NDB-01 clinical and market positioning

  • NDB-01 delivers gemcitabine and docetaxel via a gel matrix, enabling easier, faster, and safer administration in a doctor's office.

  • Phase 2 open-label study shows 90% of patients cancer-free at six months, a rate described as the highest seen in this indication.

  • Competing products from Johnson & Johnson and UroGen have higher costs ($120,000–$690,000/year) and logistical limitations; NDB-01 aims to be more convenient and cost-effective.

  • Registration study for NDB-01 is planned to start in Q2 next year, with completion targeted for 2027.

Financial overview and capital strategy

  • End of Q2 cash and equivalents totaled $20.6 million, with 33.2 million shares outstanding and an unlevered balance sheet.

  • Additional financing will be needed to support clinical milestones, but not immediately; management is mindful of share price and value creation.

  • Recent insider buying by CEO and Chief Medical Officer signals management confidence.

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Frequently asked questions

Relmada Therapeutics Inc. is a clinical-stage biotechnology company focusing on developing innovative treatments for central nervous system (CNS) diseases, with a particular emphasis on major depressive disorder. The company's flagship product, esmethadone (d-methadone, dextromethadone, REL-1017), is a novel N-methyl-D-aspartate (NMDA) receptor antagonist currently inclinical trials, aimed at serving as an adjunctive or monotherapy treatment for MDD in adults. The company is headquartered Coral Gables, Florida. Its shares are listed on the Nasdaq.

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