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Replimune Group (REPL) investor relations material
Replimune Group Q2 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2026 earnings summary6 Nov, 2025
Executive summary
Focused on developing oncolytic immunotherapies, with RP1 as the lead candidate in advanced melanoma and other skin cancers, and additional candidates RP2 and RP3 in development for broader tumor types.
FDA accepted BLA resubmission for RP1 in advanced melanoma, with a PDUFA target action date set for April 10, 2026.
Ongoing collaboration with FDA and continued progress in clinical trials for RP1, RP2, and RP3, including IGNYTE, ARTACUS, CERPASS, and REVEAL.
Financial highlights
Net loss of $83.1 million for the quarter ended September 30, 2025, compared to $53.1 million in the prior year quarter; net loss of $169.8 million for the six months ended September 30, 2025, compared to $106.8 million in the prior year period.
Operating expenses increased to $84.3 million for the quarter, driven by higher R&D and SG&A costs.
Cash, cash equivalents, and short-term investments totaled $323.6 million as of September 30, 2025, down from $483.8 million at March 31, 2025.
R&D expenses rose to $57.9 million for the quarter, up $14.4 million year-over-year.
SG&A expenses increased to $26.4 million for the quarter, up $10.9 million year-over-year.
Outlook and guidance
Current cash and investments expected to fund operations late into Q4 2026, including potential commercialization of RP1.
Expenses expected to remain high as clinical development and pre-commercialization activities continue; future capital needs may arise depending on regulatory outcomes and development progress.
How does IGNYTE-3 impact RP1 approval strategy?
What is the cash burn rate for RP1 commercialization?
What is the NMSC data's impact on RP1's market?
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Next Replimune Group earnings date
Q3 202611 Feb, 2026
Next Replimune Group earnings date
Q3 202611 Feb, 2026
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Frequently asked questions
Replimune Group Inc. is a biotechnology company focused on the development of oncolytic immunotherapies for the treatment of cancer. The company leverages its proprietary Immulytic platform to engineer viruses that selectively replicate within tumors, stimulating an immune response to attack the cancer cells. Replimune's therapies are designed to be used in combination with other immuno-oncology treatments to enhance their effectiveness. The company targets various forms of cancer, aiming to improve outcomes for patients with difficult-to-treat malignancies. The company is headquartered in Woburn, Massachusetts, and its shares are listed on the NASDAQ.
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