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Rigel Pharmaceuticals (RIGL) investor relations material
Rigel Pharmaceuticals H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary9 Sep, 2025
Business strategy and product portfolio
Focus on expanding hematology and oncology business with three commercial products: TAVALISSE, Rezlidia, and Gavreto.
Rezlidia and Gavreto were acquired to diversify and grow the portfolio, with ongoing interest in further in-licensing and acquisitions.
TAVALISSE is indicated for chronic ITP, Rezlidia for relapsed/refractory IDH1-positive AML, and Gavreto for RET fusion-positive cancers.
Strategic partnerships and collaborations are being pursued to maximize product reach and development opportunities.
Commercial performance and market opportunities
Achieved 76% year-over-year net product sales growth, with $102.5 million in sales through Q2 2025, matching 2023's full-year total.
TAVALISSE has moved from late-line to earlier-line use in ITP, with higher response rates in earlier lines.
Rezlidia and Gavreto are showing strong growth, with Gavreto's Q2 net revenues rising to $11.8 million.
International collaborations are expanding product availability and contributing to revenue growth.
Research and development pipeline
IRAC-1/4 dual inhibitor (R289) in phase 1B for lower-risk MDS, with promising safety and efficacy data and FDA fast-track and orphan designations.
Dose escalation phase for R289 completed, with dose expansion phase and further data presentations planned by year-end.
Luticidinib (Rezlidia) is being explored for glioma through collaborations and potential internal studies.
Strategic collaborations with MD Anderson and CONNECT are advancing IDH1-related research.
Gavreto: How to capture 25% untreated patients?
R289: What's the registrational path timeline?
Future product acquisitions: What are the criteria?
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Next Rigel Pharmaceuticals earnings date
Q3 20256 Nov, 2025
Next Rigel Pharmaceuticals earnings date
Q3 20256 Nov, 2025
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Frequently asked questions
Rigel Pharmaceuticals Inc. is a biotechnology company focused on discovering, developing, and commercializing small-molecule drugs for immune and hematologic disorders, as well as rare diseases. The company’s research and development efforts target critical pathways in the immune system to address conditions with significant unmet medical needs. Rigel also partners with other pharmaceutical companies to advance its therapeutic candidates. The company is headquartered in South San Francisco, California, and its shares are listed on the NASDAQ.
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