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Roivant Sciences (ROIV) investor relations material
Roivant Sciences 44th Annual J.P. Morgan Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Business evolution and strategic focus
Transitioned to a simplified, traditional development and commercialization model, prioritizing late-stage global clinical development and capital efficiency, supported by a $4.4 billion cash position.
Focused on launching three or more commercial products and achieving eight or more pivotal study readouts across six or more indications in the next 36 months.
Emphasizes creative clinical development, a unique talent model, and a culture focused on shareholder value.
Maintains flexibility for strategic transactions, only pursuing deals that align with value and timing.
Over the next decade, aims to capitalize on a simplified structure and robust pipeline.
Pipeline progress and clinical milestones
Achieved positive pivotal data for brepocitinib in dermatomyositis, with NDA filing expected early 2026 and commercial launch preparations underway.
Advanced IMVT-1402 in multiple pivotal studies for Graves’ disease, D2T RA, and other autoimmune indications, with pivotal data in 2026–2027.
Anticipates topline data for brepocitinib in NIU, phase II-B data for mosliciguat in PH-ILD in the second half of 2026, and proof-of-concept data for cutaneous sarcoidosis and CLE in 2024.
Over the next 36 months, plans for 3+ commercial launches, 4+ NDA/BLA filings, and 8+ pivotal study readouts across 6+ indications.
Rich catalyst calendar through 2028, with multiple launches, pivotal readouts, and litigation milestones.
Market opportunities and competitive positioning
Brepocitinib positioned to address significant unmet need in dermatomyositis, aiming to replace off-label therapies and IVIG.
IMVT-1402 targets late-line, autoantibody-positive RA and other autoimmune patients, with high commercial potential.
Mosliciguat offers a novel inhaled mechanism for PH-ILD, with Phase 2 data expected in 2H 2026.
Expects to build a $15+ billion portfolio by stacking multi-billion dollar opportunities across indications.
Focused on orphan-sized, high-value indications with a commercial model tailored to tractable markets.
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