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Sana Biotechnology (SANA) investor relations material
Sana Biotechnology Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Q3 2026 net income was $20.4M, driven by non-cash gains from revaluing contingent consideration and success-payment liabilities; operating expenses before those gains remained substantial.
SC451 for type 1 diabetes and SG293 for non-Hodgkin lymphoma advanced toward clinical studies; SC291 and SC262 development was suspended in the November 2025 portfolio prioritization.
Cash, cash equivalents, and marketable securities totaled $121.7M at September 30, 2026; expected runway was into mid-2027.
Financial highlights
Q3 GAAP net income was $20.4M, or $0.07 per share; 9M GAAP net loss was $90.4M, or $0.31 per share.
Q3 non-GAAP net loss was $43.0M, or $0.14 per share; 9M non-GAAP net loss was $121.5M, or $0.41 per share.
Q3 R&D expense was $33.9M, up $3.8M YoY; G&A was $10.9M, versus $10.3M. 9M R&D and G&A were $93.4M and $33.2M, respectively.
Q3 operating expenses were negative $18.5M versus $43.5M a year earlier, reflecting a $63.4M non-cash gain from liability and contingent-consideration fair-value changes.
9M net loss narrowed from $185.3M to $90.4M; 2025 included a $44.6M long-lived asset impairment, while 2026 recorded net gains on liability revaluations.
Outlook and guidance
SC451 IND filing and Phase 1/2 trial are targeted as early as 2026; SG293 clinical study is targeted for 1Q 2027, with first-in-human data possible in H1 2027.
Data from SC451 and SG293 are anticipated in 2027; both programs are viewed as having potential for relatively rapid proof of concept.
SG227 clinical testing could begin as early as 2027, contingent on SG293’s early clinical profile.
Excluding one-time items, 2026 R&D expense is expected to be materially flat or slightly lower than 2025, with G&A materially flat.
- IND and phase I/II trial for diabetes therapy and first-in-human CAR T data expected within 12 months.SANA
H.C. Wainwright 28th Annual Global Investment Conference - Gene-edited islet therapy for type 1 diabetes nears clinical trial, with CAR T data expected in 2027.SANA
Morgan Stanley 24th Annual Global Healthcare Conference - Hypoimmune cell therapy for diabetes nears trials; in vivo CAR T data expected in 2027.SANA
Citigroup’s Biopharma Back to School Summit 2026 - Advancing gene-modified islet and in vivo CAR T therapies, with key trials and data expected soon.SANA
Wells Fargo 21st Annual Healthcare Conference - Hypoimmune cell and in vivo CAR T platforms advance toward clinical trials for diabetes and cancer.SANA
Corporate presentation - Advancing hypoimmune cell therapies for T1D and in vivo CAR T cells, with key trials in 2026.SANA
Corporate presentation - Net loss narrowed, clinical readiness advanced, and cash runway projected into mid-2027.SANA
Q2 2026 - Immune-evasive cell therapies show promise for diabetes and CAR T programs advance toward clinical milestones.SANA
H.C. Wainwright 27th Annual Global Investment Conference - Gene-edited cell therapy enabled insulin independence and advances toward key milestones in 2025.SANA
43rd Annual J.P. Morgan Healthcare Conference 2025
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