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Sana Biotechnology
Sana Biotechnology (SANA) investor relations material
Sana Biotechnology H.C. Wainwright 28th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 28th Annual Global Investment Conference summary15 Sep, 2026
Strategic partnerships and platform overview
Entered a collaboration with Mayo Clinic, providing equity investment and clinical trial support for SC451.
Developing two main platforms: a hypoimmune cell therapy for type 1 diabetes and an in vivo CAR T platform targeting cancer and autoimmune diseases.
The hypoimmune platform aims for a one-time, immunosuppression-free treatment for type 1 diabetes.
The in vivo CAR T platform seeks to eliminate conditioning chemotherapy and improve manufacturability and safety.
Type 1 diabetes program progress
Preparing to file an IND for SC451 and initiate a phase I/II trial by year-end.
Previous IIT study (UP421) in Sweden met all primary and secondary endpoints, showing 14 months of islet cell survival without immunosuppression.
SC451 will use stem cell-derived islets, aiming for scalable manufacturing and intramuscular delivery.
Key next steps include completing GLP toxicology, GMP tech transfer, and scaling up manufacturing.
Early clinical success will be measured by immune evasion and insulin production within 28 days, with longer-term insulin independence as a goal.
In vivo CAR T platform advancements
Lead program SG293 targets non-Hodgkin's lymphoma, with first-in-human data expected in the first half of 2027.
The fusosome vector system enables cell-specific delivery and integration, aiming to reduce off-target toxicity and allow redosing.
Platform refinements include minimizing CAR surface expression to lower immunogenicity and improve manufacturability.
NHP studies showed significant CAR T expansion, B cell depletion, and evidence of B cell reset.
SG227, a BCMA-directed CAR T, is also advancing, with plans to expand into multiple myeloma and autoimmune diseases.
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Latest events from Sana Biotechnology
- Gene-edited islet therapy for type 1 diabetes nears clinical trial, with CAR T data expected in 2027.SANA
Morgan Stanley 24th Annual Global Healthcare Conference - Hypoimmune cell therapy for diabetes nears trials; in vivo CAR T data expected in 2027.SANACitigroup’s Biopharma Back to School Summit 2026
- Advancing gene-modified islet and in vivo CAR T therapies, with key trials and data expected soon.SANAWells Fargo 21st Annual Healthcare Conference
- Hypoimmune cell and in vivo CAR T platforms advance toward clinical trials for diabetes and cancer.SANACorporate presentation
- Advancing hypoimmune cell therapies for T1D and in vivo CAR T cells, with key trials in 2026.SANACorporate presentation
- Net loss narrowed, clinical readiness advanced, and cash runway projected into mid-2027.SANAQ2 2026
- Immune-evasive cell therapies show promise for diabetes and CAR T programs advance toward clinical milestones.SANAH.C. Wainwright 27th Annual Global Investment Conference
- Allogeneic cell therapy is poised for broad impact, with pivotal trials and scalable innovation underway.SANAGoldman Sachs Cell Therapy Day
- Gene-edited cell therapy enabled insulin independence and advances toward key milestones in 2025.SANA43rd Annual J.P. Morgan Healthcare Conference 2025
Next Sana Biotechnology earnings date
Q3 202610 Nov, 2026
Sana Biotechnology
Next Sana Biotechnology earnings date
Q3 202610 Nov, 2026
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Frequently asked questions
Sana Biotechnology Inc. is a biotechnology company focusing on the development of engineered cells as medicines. The company focuses on both ex vivo and in vivo cell engineering platforms to address a variety of therapeutic areas with significant unmet needs, including oncology, diabetes, central nervous system disorders, and autoimmune diseases among others. Sana Biotechnology's approach involves the use of cutting-edge technologies such as CRISPR for gene editing and their proprietary platforms, Fusogen for in vivo cell engineering, and a hyperimmune platform for ex vivo cell engineering. They are actively investigating potential treatments for conditions such as non-Hodgkin lymphoma, acute lymphoblastic leukemia, chronic lymphocytic leukemia, multiple myeloma, and diabetes, to name a few. The company is headquartered in Seattle, Washington, and its shares are listed on the NASDAQ.