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Seer (SEER) investor relations material
Seer Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
2025 revenue reached $16.6 million, up 17% year-over-year, with Q4 revenue at $4.2 million and a 67% increase in installed base to 82 instruments.
Consumable kit volume rose 69% year-over-year, and cumulative publications nearly doubled, reflecting strong scientific validation.
Launched ProVue Lung, a proteomics-based LDT for early lung cancer detection, and enabled the first diagnostic test on the platform.
Ended 2025 with $241 million in cash, cash equivalents, and investments, maintaining disciplined expense management and no debt.
Results were impacted by delayed NIH funding, budgetary pressures, and cautious customer spending.
Financial highlights
Q4 2025 revenue was $4.2 million, up 5% year-over-year; full year revenue was $16.6 million, up from $14.2 million in 2024.
Gross margin for Q4 2025 was 52%, and for the full year was 51%.
Operating expenses for 2025 were $86.5 million, down 19% year-over-year.
Net loss for 2025 was $73.6 million, improved from $86.6 million in 2024.
Free cash flow loss improved to $45.6 million from $49.4 million in 2024.
Outlook and guidance
2026 revenue guidance is $16–18 million, representing approximately 3% growth at the midpoint.
Guidance reflects ongoing pressure on instrument placements and project funding due to uncertain NIH funding.
Growth catalysts include new product innovation, expanded installed base utilization, and leadership in AI-driven proteomics.
Potential upside exists if additional population-scale studies are secured in 2026.
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