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Senti Biosciences (SNTI) investor relations material
Senti Biosciences Registration filing summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Company overview and business model
Clinical-stage biotechnology company developing next-generation cell and gene therapies using proprietary gene circuit platform technologies for incurable diseases.
Focus on engineering CAR-NK cells to target cancer, aiming for high specificity and control over therapeutic effects.
Mission centers on creating smarter medicines that can sense, compute, and respond to complex disease environments.
Financial performance and metrics
As of March 31, 2026, net tangible book value was $(10.0) million, or $(0.32) per share, with 31,144,754 shares outstanding.
After the offering, pro forma net tangible book value would be $(0.6) million, or $(0.01) per share, with immediate dilution of $0.64 per share to new investors.
Company has incurred recurring losses, negative cash flows, and has an accumulated deficit, raising substantial doubt about its ability to continue as a going concern.
Use of proceeds and capital allocation
Will not receive proceeds from the resale of shares by the selling securityholder; received approximately $9.7 million in net proceeds from the issuance of convertible notes.
- Q1 2026 saw SENTI-202 clinical progress, narrowed net loss, and new $40M financing.SNTI
Q1 202614 May 2026 - SENTI-202 achieved 50% ORR and 42% CR/CRh with excellent safety in R/R AML Phase 1 trial.SNTI
Corporate presentation9 Apr 2026 - Positive SENTI-202 clinical progress, RMAT status, and $61.4M net loss with $16.4M cash.SNTI
Q4 202527 Mar 2026 - SENTI-202 achieved 42% CR/CRh in AML with strong safety and rapid recovery, advancing to pivotal trials.SNTI
Leerink Global Healthcare Conference 20269 Mar 2026 - SENTI-202 delivers deep, durable AML responses with broad eligibility and strong clinical momentum.SNTI
TD Cowen 46th Annual Health Care Conference3 Mar 2026 - SENTI-202 and SENTI-301A advance clinical cell therapies with Logic Gate technology for cancer.SNTI
H.C. Wainwright 26th Annual Global Investment Conference 202421 Jan 2026 - Multi-target cell therapies advance in AML and liver cancer, with key data readouts ahead.SNTI
Chardan's 8th Annual Genetic Medicines Conference20 Jan 2026 - SENTI-202 demonstrates durable, selective efficacy in AML, with expansion into solid tumors planned.SNTI
H.C. Wainwright 27th Annual Global Investment Conference31 Dec 2025 - Biotech seeks $300M via shelf, faces going concern risk and dilution; Leerink Partners leads ATM.SNTI
Registration Filing16 Dec 2025
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