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Seres Therapeutics (MCRB) investor relations material
Seres Therapeutics Piper Sandler 37th Annual Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Piper Sandler 37th Annual Healthcare Conference summary2 Dec, 2025
Microbiome technology and therapeutic platform
Developed a platform to design bacterial consortia drugs targeting specific disease pathways, with two Breakthrough Therapy designations for VOWST and SER-155.
Manufacturing expertise includes cultivating novel bacteria, regulatory precedent with FDA, and advanced CMC processes for drug stability and cost efficiency.
SER-155 clinical development and unmet need
SER-155 targets infection, bacteremia, and graft-versus-host disease in allo-HSCT patients, addressing high infection rates and mortality.
Phase Ib data showed a 77% reduction in bloodstream infection risk, lower antibiotic use, and positive biomarker results.
FDA provided constructive feedback, agreeing on key phase II design elements, including endpoints, study size, and interim analysis.
Interim analysis may allow early pivotal study transition if efficacy is strong; safety profile in phase I was similar to placebo.
Commercial opportunity and pricing
Allo-HSCT market includes 40,000 annual transplants globally, concentrated in specialized centers for efficient outreach.
Protocol-driven care enables rapid adoption; strong value proposition due to high infection costs and outpatient reimbursement.
Comparable product PREVYMIS is priced at $25,000–$27,000 per course and has seen rapid uptake.
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Next Seres Therapeutics earnings date
Q4 20256 Mar, 2026
Next Seres Therapeutics earnings date
Q4 20256 Mar, 2026
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Frequently asked questions
Seres Therapeutics, Inc. is a microbiome therapeutics platform company that engages in developing bacterial consortia that are designed to functionally interact with host cells and tissues to treat disease. The company's lead product candidate is the SER-109, an oral microbiome therapeutic candidate which has completed Phase III clinical trial for the treatment of CDI. It also develops SER-155 and SER-287 which are in Phase Ib clinical trial to reduce incidences of gastrointestinal infections and ulcerative colitis; SER-301 that is in Phase Ib clinical trial to treat metastatic melanoma; and SER-262 to treat Clostridioides difficile infection.
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