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Sernova Biotherapeutics (SVA) investor relations material

Sernova Biotherapeutics Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary14 Sep, 2025

Executive summary

  • Focused on regenerative medicine, advancing the Cell Pouch Bio-hybrid Organ for chronic diseases, with lead programs in type 1 diabetes, hypothyroidism, and hemophilia A.

  • Phase 1/2 clinical trial in type 1 diabetes shows 8 of 12 patients achieving insulin independence, with sustained results in some cases over 4 years.

  • Strategic partnerships with Evotec (iPSC-based islet clusters) and Eledon Pharmaceuticals (immunosuppressive agent) support pipeline development.

  • FDA IND approval received for hypothyroidism program; preclinical progress in hemophilia A.

Financial highlights

  • Net loss for the nine months ended July 31, 2025 was $13.5 million, a significant decrease from $27.2 million in the prior year period.

  • Research and development expenses decreased by $13.3 million year-over-year, reflecting cost-saving measures and reduced activity in the iPSC program.

  • General and administrative expenses also declined by $1.1 million year-over-year due to lower legal, professional, and investor relations costs.

  • Cash at July 31, 2025 was $84 thousand, with a working capital deficit of $23.9 million.

  • Financing activities provided $4.8 million in the nine months ended July 31, 2025, mainly from a $4 million loan and $1.2 million in debenture financing.

Outlook and guidance

  • Material uncertainty exists regarding the ability to continue as a going concern; additional funding is required before the end of September 2025 to meet obligations and continue R&D.

  • Management is actively seeking new financing through equity, loans, or strategic alliances.

  • Planned cost reductions and deferral of expenditures until sufficient funding is secured.

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Frequently asked questions

Sernova Corp is a biotechnology company focused on developing cell therapy solutions for the treatment of chronic diseases, including diabetes, hemophilia, and thyroid disorders. The company’s lead technology, the Cell Pouch System, is an implantable device designed to house therapeutic cells that can produce essential proteins or hormones, potentially offering a functional cure for diseases such as type 1 diabetes. The company is headquartered in London, Canada, and its shares are listed on the TSX and OTCQB.

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