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Sol-Gel Technologies (SLGL) investor relations material

Sol-Gel Technologies Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary20 Nov, 2025

Executive summary

  • Announced Q3 2025 results, highlighting progress in late-stage pipeline for rare dermatologic diseases and expansion of commercial partnerships for approved products.

  • Health Canada approved EPSOLAY for rosacea; new licensing agreements signed for EPSOLAY and TWYNEO in Australia and New Zealand.

  • Ongoing pivotal Phase 3 trial for SGT-610 in Gorlin syndrome, with top-line results expected Q4 2026; exploring high-frequency BCC as an additional indication.

Financial highlights

  • Q3 2025 revenue was $0.4 million, down from $5.4 million in Q3 2024, mainly due to lower licensing and royalty income.

  • Research and development expenses rose to $5.7 million from $4.8 million year-over-year, driven by SGT-610 development and clinical trial costs.

  • General and administrative expenses decreased to $1 million from $1.4 million, reflecting cost-saving measures.

  • Net loss for Q3 2025 was $5.9 million ($2.13 per share), compared to a net loss of $0.4 million ($0.13 per share) in Q3 2024.

  • Cash, cash equivalents, and marketable securities totaled $20.9 million as of September 30, 2025.

Outlook and guidance

  • TWYNEO and EPSOLAY expected to launch in most new territories in 2028 and 2027, respectively.

  • Anticipated annual royalty revenue from these launches could reach $10 million by 2031.

  • Cash resources projected to fund operations into Q1 2027.

  • Targeting $10 million EBITDA from ex-U.S. business by 2031.

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Frequently asked questions

Sol-Gel Technologies Ltd., a clinical stage specialty pharmaceutical company, focuses on developing and commercializing topical dermatological drug products based on its proprietary microencapsulation delivery system. The company offers Phase 5 (clobex), a prescription liquid medication designed to selectively target specific classes of dendritic cells that initiate the immune response. Its smevetch is a topical compounded drug that contains tacrolimus and dexamethasone. The company was formerly known as Silex Platform Limited and changed its name to Sol-Gel Technologies Ltd. in June 2010. Sol-Gel Technologies Ltd. is based in London, the United Kingdom.

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