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Soligenix (SNGX) investor relations material

Soligenix Corporate Presentation summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Corporate Presentation summary19 Sep, 2025

Company overview and strategy

  • Focuses on developing and commercializing therapies for rare diseases with unmet medical needs, targeting both orphan diseases in oncology/inflammation and public health threats like ricin and viral diseases.

  • Operates two segments: Specialized BioTherapeutics for orphan diseases and Public Health Solutions for vaccines/therapeutics for military and civilian use.

  • Pipeline includes multiple fast track and orphan designated products, aiming for ~$2B in global annual sales.

Pipeline and clinical progress

  • HyBryte (synthetic hypericin sodium) for cutaneous T-cell lymphoma (CTCL) showed positive Phase 3 results; a second confirmatory Phase 3 trial is enrolling, with FDA and EMA engagement ongoing.

  • SGX302 for mild-to-moderate psoriasis demonstrated positive proof-of-concept and ongoing Phase 2a trial; targets a >$1B global market.

  • SGX945 for Behçet's disease completed Phase 2a with biological efficacy and safety; estimated market >$200M.

  • Public Health Solutions segment includes RiVax (ricin vaccine), SuVax/MarVax (filovirus vaccines), and CiVax (COVID-19 vaccine), all supported by significant NIH funding.

Market opportunity and commercialization

  • HyBryte addresses a $250M global market for CTCL, with rapid response and favorable safety profile compared to existing therapies.

  • SGX302 targets the large, underserved mild-to-moderate psoriasis market, with potential for both clinic and home use.

  • SGX945 offers a new option for Behçet's disease, where current treatments are often ineffective or poorly tolerated.

  • Public health vaccines have potential for government procurement and up to 3 Priority Review Vouchers, each valued at ~$100M.

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Q3 202510 Nov, 2025
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Frequently asked questions

Soligenix Inc is a U.S.-based biopharmaceutical company focused on developing and commercializing treatments for rare diseases and biodefense indications. The company works on therapies for inflammatory conditions, oncology, and infectious diseases, with both proprietary drug candidates and government-supported programs. The company is headquartered in Princeton, New Jersey, and its shares are listed on the NASDAQ.

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