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SpringWorks Therapeutics (SWTX) investor relations material
SpringWorks Therapeutics Q1 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q1 2025 earnings summary8 May, 2025
Executive summary
SpringWorks Therapeutics is a commercial-stage biopharma focused on rare diseases and oncology, with two FDA-approved products: OGSIVEO and GOMEKLI, and a pipeline of clinical and preclinical candidates.
OGSIVEO (nirogacestat) is approved for adult desmoid tumors; GOMEKLI (mirdametinib) is approved for NF1-associated plexiform neurofibromas in adults and children.
On April 27, 2025, SpringWorks entered into a merger agreement to be acquired by Merck KGaA, Darmstadt, Germany, for $47.00 per share in cash, pending customary closing conditions.
Financial highlights
Net product revenue for Q1 2025 was $49.1 million, up 134% year-over-year from $21.0 million in Q1 2024, driven by OGSIVEO and GOMEKLI launches.
Net loss for Q1 2025 was $83.2 million, compared to $87.4 million in Q1 2024, a 5% improvement.
Cash, cash equivalents, and marketable securities totaled $382.7 million as of March 31, 2025, down from $461.9 million at year-end 2024.
Operating expenses increased to $129.6 million in Q1 2025 from $114.9 million in Q1 2024, mainly due to higher SG&A costs for commercialization.
Net cash used in operating activities was $68.8 million for Q1 2025, compared to $78.9 million in Q1 2024.
Outlook and guidance
Management expects current liquidity to fund operations for at least twelve months from the reporting date.
Profitability is anticipated in the first half of 2026, contingent on continued commercial success of OGSIVEO and GOMEKLI.
Pre-commercial preparations for OGSIVEO and GOMEKLI are underway in Europe, with regulatory decisions expected in 2025.
What is the status of the MAA for nirogacestat?
What are the expected wind-down costs for MapKure?
What are the restrictions on business activities?
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Frequently asked questions
SpringWorks Therapeutics Inc. is a biopharmaceutical company focused on developing life-changing medicines for patients with severe rare diseases and cancer. The company leverages a precision medicine approach to develop therapies that target critical pathways in these diseases. SpringWorks' portfolio includes investigational therapies designed to modulate the activity of key proteins and signaling pathways involved in disease progression. The company collaborates with other pharmaceutical firms and research institutions to advance its clinical programs and bring innovative treatments to market. The company is headquartered in Stamford, Connecticut, and its shares are listed on the NASDAQ.
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