Supernus Pharmaceuticals
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Supernus Pharmaceuticals (SUPN) investor relations material

Supernus Pharmaceuticals Barclays 28th Annual Global Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Barclays 28th Annual Global Healthcare Conference summary11 Mar, 2026

Key accomplishments and portfolio transformation

  • Achieved record revenue in 2025, completing transition from legacy products losing exclusivity.

  • Sage Therapeutics acquisition and addition of Zurzuvae marked a major portfolio expansion.

  • ONAPGO launch exceeded expectations, driving strong demand despite supply constraints.

  • Four main growth drivers—Qelbree, Gocovri, Zurzuvae, ONAPGO—delivered over 20% growth in Q4 2025.

  • Stock price rose 80% in six months, reflecting market recognition of portfolio reconfiguration.

Product performance and differentiation

  • Qelbree scripts grew 18% in Q4 and 21% for 2025, driven by its rapid onset and non-stimulant profile.

  • Gocovri is uniquely approved for both OFF episodes and dyskinesia in Parkinson’s, with double-digit growth.

  • Zurzuvae is the only oral treatment for postpartum depression, showing rapid onset and short therapy duration.

  • ONAPGO’s strong launch revealed broader patient uptake than expected, with supply issues now addressed for 2026.

Commercial strategy and market opportunity

  • Qelbree’s market share remains small relative to the ADHD market, indicating significant growth potential.

  • Physician education and targeted marketing are key to shifting prescribing habits toward non-stimulants.

  • Balanced growth expected across all four main products in 2026, with ONAPGO guided at $45M–$70M in sales.

  • Zurzuvae’s market opportunity is large, with only 20,000 patients treated out of 500,000 annual cases.

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Frequently asked questions

Supernus Pharmaceuticals Inc. is a biopharmaceutical company focused on the development and commercialization of treatments for central nervous system (CNS) disorders. The company specializes in therapies for neurological and psychiatric conditions, including epilepsy, attention deficit hyperactivity disorder (ADHD), and depression. Supernus Pharmaceuticals Inc. is headquartered in Rockville, Maryland, and its shares are listed on the NASDAQ.

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