)
Visual21 Nov 2025
Data center suppliers
Surrozen (SRZN) investor relations material
Surrozen Guggenheim Securities 2nd Annual Healthcare Innovation Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Guggenheim Securities 2nd Annual Healthcare Innovation Conference summary12 Nov, 2025
Scientific and clinical background
Focus on Wnt pathway activation for tissue regeneration, particularly in ophthalmology, due to strong genetic and clinical evidence in retinal diseases.
Wnt pathway activation offers VEGF-like efficacy in retinal diseases, with potential for greater benefit when combined with VEGF and IL-6 inhibition.
Preclinical models show synergy and superior efficacy when combining Wnt agonism with VEGF inhibition, outperforming single-mechanism approaches.
Wnt biology is prioritized for diabetic macular edema (DME) due to clearer biological rationale, but wet AMD remains a target.
Safety profile for Wnt agonists is favorable, with no significant clinical safety signals reported to date.
Pipeline and partnerships
Lead molecule 8141 (Wnt/VEGF) is on track for IND filing in 2026, with 8143 (Wnt/VEGF/IL-6) following a few months later.
8141 and 8143 are designed for both DME and wet AMD, with initial trials likely to include both indications and focus on treatment-naive patients.
Partnership with Boehringer Ingelheim (BI) involves a licensed molecule more potent than Merck’s RESTRA; BI’s program is now a straight license with limited information sharing.
Preclinical data suggest combining mechanisms in a single molecule is more effective than separate injections.
Intellectual property position is strong, with broad patents covering multivalent antibodies targeting Frizzled LRP5/6.
Competitive landscape and expectations
Merck and Roche are key competitors, with Merck’s RESTRA studies (Brunello and Barolo) expected to read out in Q3 next year.
Clinical feedback highlights the need for improved retinal drying and visual function, areas where Wnt-based therapies may excel.
Monthly dosing for RESTRA is limited by formulation constraints; 8141 aims for less frequent dosing (every 8–12 weeks).
Anticipated additive benefits from combining Wnt, VEGF, and IL-6 mechanisms, supported by recent clinical data.
Company positions itself as a scientific leader in Wnt biology, with opportunities to educate clinicians and differentiate from competitors.
Partial view of Summaries dataset, powered by Quartr API
Research faster. Power your platform.
Next Surrozen earnings date
Q4 202520 Mar, 2026
The essential earnings season companion
The #1 app for qualitative research. Live earnings calls, AI chat, transcripts, and more. All for free.
Live calls and transcripts
Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.
Find what you need faster
Search for any keyword across all transcripts simultaneously.
Easily store key findings
Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Your watchlist. Your dashboard.
Follow the companies that matter to you. Get a personalized feed with real-time updates.
Be the first to know
Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.
Consensus estimates
Access analyst consensus estimates, valuation multiples, and revenue segments splits.
All IR material in one place
The easiest way to stay updated during earnings season.
Global coverage
All events from public companies. Live and recorded.
Just click and listen
No webcast links. No manual registrations.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
)
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
)
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
anuj283App Store
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
anuj283App Store
I can't remember the last time an app had such a positive impact on my investment process.
)
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
@theshortbearx.com
I can't remember the last time an app had such a positive impact on my investment process.
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
@theshortbearx.com
)
)
Frequently asked questions
Surrozen Inc., established in 2015, is a clinical-stage biotechnology firm at the forefront of developing novel therapeutics designed to selectively modulate the Wnt pathway for tissue repair and regeneration. The company's innovative approach involves the creation of targeted regenerative antibodies intended to repair a wide array of tissues and restore organ function damaged by serious diseases. Surrozen leverages advanced antibody engineering techniques and a deep understanding of Wnt pathway biology across various disease settings to design tissue-specific antibodies. These antibodies have the potential to regenerate tissue in a multitude of organs and tissues, addressing diseases such as liver, intestine, retinal, lacrimal gland, lung, cornea, pancreas, skin, and many others. The company is headquartered in South San Francisco, California, and its shares are listed on the Nasdaq.
Quartr provides global coverage of all investor relation material from public companies.
Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.
Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.
Yes, the Quartr mobile app is free on both iOS and Android.
Yes. Quartr provides global, industry-leading live coverage of company events such as regular earnings calls, capital markets days, M&A announcements, and investor conferences. Live with zero delays. Just click and listen.
Yes, capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Yes. Follow the companies that matter to you. Get a personalized feed with real-time updates, a tailored earnings calendar, and instant alerts when earnings calls go live.
Yes. Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned, regardless of who's talking.
Explore our global coverage