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SynAct Pharma (SYNACT) investor relations material
SynAct Pharma Aktiedagarna 2026 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Strategic focus and therapeutic approach
Shifted focus to developing pro-resolution therapies for immune system diseases, targeting both chronic and acute inflammatory conditions.
Pro-resolution immunology aims to modulate immune cells without immunosuppression, potentially reducing side effects compared to current treatments.
Lead compound, resomelagon (AP1189), is a once-daily oral therapy with a novel, non-immunosuppressive mechanism.
Clinical development and pipeline
Lead program is in phase II-B for rheumatoid arthritis, with top-line data expected in June.
Pipeline includes additional trials in respiratory viral infections and dengue, leveraging the broad applicability of the mechanism.
Animal models and ongoing clinical programs support potential efficacy across multiple indications.
Market opportunity and positioning
Addressing a large market, with rheumatoid arthritis and related indications representing a $26–30 billion opportunity.
Targeting patients who do not respond to first-line therapies, aiming to delay or avoid progression to expensive biologics.
Non-immunosuppressive profile could allow earlier intervention and improved safety.
- ADVANCE Phase 2b RA study completed dosing; cash runway extended after SEK 51.9M share issue.SYNACT
Q1 202627 May 2026 - Upcoming clinical data and strong financials position the pipeline for major partnering deals.SYNACT
CMD 202611 Mar 2026 - R&D-driven losses deepened in 2025, but major clinical milestones set up a transformative 2026.SYNACT
Q4 202518 Feb 2026 - ADVANCE Phase 2b study for resomelagon in high-activity RA targets data and deals by 2025.SYNACT
CMD 202420 Jan 2026 - Phase IIB results for a novel immune-modulating therapy in RA and viral infections expected next year.SYNACT
Life Science Summit 202524 Dec 2025 - RA Phase 2B data expected year-end; pipeline expanded, funding secured through 2026.SYNACT
CMD 202519 Nov 2025 - Losses widened on higher R&D, but financing extended cash runway into 2027.SYNACT
Q3 202530 Oct 2025 - ADVANCE Phase 2b RA study progresses, financial runway extended into 2027 via new funding.SYNACT
Q2 202520 Aug 2025 - ADVANCE Phase 2b study launched; liquidity shortfall requires new capital for continued operations.SYNACT
Q3 202413 Jun 2025
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