Logotype for Synlogic Inc

Synlogic (SYBX) investor relations material

Synlogic Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Logotype for Synlogic Inc
Q2 2025 earnings summary7 Aug, 2025

Executive summary

  • Discontinued lead Phase 3 trial (Synpheny-3) for PKU in February 2024 after internal review indicated unlikely success; strategic alternatives including merger or sale are being actively pursued.

  • Corporate restructuring reduced workforce to one full-time employee, with consultants supporting ongoing operations and strategic review.

  • No product revenue generated; focus remains on maximizing shareholder value through potential transactions.

Financial highlights

  • Net loss of $0.5 million for Q2 2025, compared to net income of $3.1 million in Q2 2024; net loss of $0.2 million for the six months ended June 30, 2025, versus $22.5 million loss in the prior year period.

  • Research and development expenses dropped to $0.01 million in Q2 2025 from $2.2 million in Q2 2024, reflecting the discontinued trial and restructuring.

  • General and administrative expenses decreased to $0.8 million in Q2 2025 from $1.2 million in Q2 2024 due to lower headcount and professional fees.

  • Restructuring and other charges were a gain of $0.01 million in Q2 2025, compared to a $3.8 million gain in Q2 2024, mainly from asset sales and lease termination.

  • Cash and cash equivalents were $17.0 million as of June 30, 2025, down from $19.8 million at year-end 2024.

Outlook and guidance

  • Current cash and cash equivalents expected to fund operations at current levels for at least the next 12 months.

  • Expenses anticipated to remain low in the near term as the company continues to evaluate strategic alternatives.

  • No expectation of product revenue unless regulatory approval is achieved or a strategic transaction is completed.

Partial view of Summaries dataset, powered by Quartr API
Research faster. Power your platform.

Next Synlogic earnings date

Logotype for Synlogic Inc
Q3 202511 Nov, 2025
Your earnings 
season toolkit.
Download
Free on both iOS & Android.

Next Synlogic earnings date

Logotype for Synlogic Inc
Q3 202511 Nov, 2025

The essential earnings season companion

The #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.

Live calls and transcripts

Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.

Find what you need faster

Search for any keyword across all transcripts simultaneously.

Easily store key findings

Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.

Your watchlist. Your dashboard.

Follow the companies that matter to you. Get a personalized feed with real-time updates.

Be the first to know

Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.

Consensus estimates

Access analyst consensus estimates, valuation multiples, and revenue segments splits.

All IR material in one place

The easiest way to stay updated during earnings season.

Global coverage

All events from public companies. Live and recorded.

Just click and listen

No webcast links. No manual registrations.

Research anytime, anywhere

Built for professionals. Loved by everyone. Try our free mobile app.

excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
App-store-avatar.png play-store-avatar.png
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
play-store-avatar
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
App-store-avatar.png play-store-avatar.png
anuj283App Store
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
App-store-avatar.png play-store-avatar.png
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
play-store-avatar
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
App-store-avatar.png play-store-avatar.png
anuj283App Store
I can't remember the last time an app had such a positive impact on my investment process.
x-avatar
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
App-store-avatar.png play-store-avatar.png
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
x-avatar
@theshortbearx.com
I can't remember the last time an app had such a positive impact on my investment process.
x-avatar
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
App-store-avatar.png play-store-avatar.png
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
x-avatar
@theshortbearx.com

Frequently asked questions

Synlogic Inc. is a biotechnology company focused on developing synthetic biotic medicines, which are engineered living organisms designed to treat metabolic and other diseases. The company’s platform uses genetically modified bacteria to deliver therapeutic effects within the human body, targeting diseases such as phenylketonuria (PKU) and other metabolic disorders. Synlogic’s approach aims to address unmet medical needs through innovative treatments that leverage the power of synthetic biology. The company is headquartered in Cambridge, Massachusetts, and its shares are listed on the NASDAQ.

Quartr provides global coverage of all investor relation material from public companies.

  • Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.

  • Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.

  • Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.

Yes, the Quartr mobile app is free on both iOS and Android.

Yes. Quartr provides global, industry-leading live coverage of company events such as regular earnings calls, capital markets days, M&A announcements, and investor conferences. Live with zero delays. Just click and listen.

Yes, capturing important takeaways is as simple as it gets. Even during your lunch run or commute.

Yes. Follow the companies that matter to you. Get a personalized feed with real-time updates, a tailored earnings calendar, and instant alerts when earnings calls go live.

Yes. Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned, regardless of who's talking.

Explore our global coverage