Syntara
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Syntara (SNT) investor relations material

Syntara Q1 2027 TU earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q1 2027 TU earnings summary29 Oct, 2026

Executive summary

  • Phase 2 SNT-4728 results showed reduced putamen inflammation and statistically significant improvement in clinician-assessed motor signs 12 weeks after treatment ended.

  • AZALOX advanced to its final Phase 1b dose cohort; a $4.7 million R&D tax incentive supported development programs, and quarter-end cash was $14.1 million.

Financial highlights

  • Cash and cash equivalents were $14.060 million at 30 September 2026, versus $13.562 million at 30 June 2026; net operating cash inflow was $649,000.

  • Operating cash outflows included $1.989 million for R&D, $1.787 million for staff and $597,000 for administration and corporate costs; R&D and staff represented 89% of net operating cash outflows.

Outlook and guidance

  • AZALOX is expected to progress to a Phase 2 component evaluating the selected amsulostat dose in ~30 patients, subject to completion and review of final-cohort safety data.

  • SNT-9465 top-line results are expected in Q1 2027; preliminary MESSAGE study results are anticipated in H1 2027.

  • Further SNT-4728 analyses of digital endpoints and clinical, biological and imaging biomarkers remain outstanding; additional studies are needed to establish clinical benefit and any effect on disease progression.

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