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Syntara (SNT) investor relations material
Syntara Q1 2027 TU earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Phase 2 SNT-4728 results showed reduced putamen inflammation and statistically significant improvement in clinician-assessed motor signs 12 weeks after treatment ended.
AZALOX advanced to its final Phase 1b dose cohort; a $4.7 million R&D tax incentive supported development programs, and quarter-end cash was $14.1 million.
Financial highlights
Cash and cash equivalents were $14.060 million at 30 September 2026, versus $13.562 million at 30 June 2026; net operating cash inflow was $649,000.
Operating cash outflows included $1.989 million for R&D, $1.787 million for staff and $597,000 for administration and corporate costs; R&D and staff represented 89% of net operating cash outflows.
Outlook and guidance
AZALOX is expected to progress to a Phase 2 component evaluating the selected amsulostat dose in ~30 patients, subject to completion and review of final-cohort safety data.
SNT-9465 top-line results are expected in Q1 2027; preliminary MESSAGE study results are anticipated in H1 2027.
Further SNT-4728 analyses of digital endpoints and clinical, biological and imaging biomarkers remain outstanding; additional studies are needed to establish clinical benefit and any effect on disease progression.
- Amsulostat leads a three-asset pipeline with near-term clinical catalysts.SNT
Investor presentation - Net loss widened to $9.0 million as revenue fell and new equity raised $8.8 million.SNT
H2 2026 - FDA-backed late-stage trials and strong cash position set up major clinical catalysts in H2 2026.SNT
Q4 2026 TU - Shareholders voted on two share placement resolutions, with results to be announced later today.SNT
EGM 2026 - Phase II/2a trial of SNT-4728 targets neuroinflammation in iRBD, results due by June or 2026.SNT
Status update - FDA supports Phase 2b for amsulostat; cash runway extended after A$8m placement.SNT
Q3 2026 TU - FDA backs Phase 2b amsulostat trial; funding secured for key 2026 milestones.SNT
Investor update - 73% achieved TSS50 and 44% SVR25 with strong tolerability and ongoing development plans.SNT
Study Update - Phase 2 myelofibrosis trial fully recruited; A$5m raised; interim data due December 2024.SNT
Q1 2025 TU
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