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TG Therapeutics (TGTX) investor relations material
TG Therapeutics H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary8 Sep, 2025
Market landscape and product differentiation
Relapsing MS affects nearly a million in the US, with 300,000–400,000 treated and 80,000 seeking new therapies annually.
About half of new MS patients start on anti-CD20 monoclonal antibodies, with three main drugs in the class.
Differentiation in the IV segment includes a one-hour infusion time versus competitors’ 2–3.5 hours and a 20–25% lower cost.
Majority of patients (65%) choose IV over subcutaneous options, with a subcutaneous formulation in development.
Commercial performance and growth strategy
2025 revenue guidance raised to $570–$575 million, based on new patient starts and therapy persistence.
Market share in the IV segment has grown from 25% to nearly one-third.
Most new patients are switches from other therapies, with switchers outnumbering newly diagnosed cases.
Direct-to-patient marketing, including TV campaigns, was recently launched to boost awareness.
Clinical experience and patient outcomes
Real-world data shows strong efficacy and improved tolerability, especially lower infusion reaction rates after the first dose.
Use of Tylenol in practice has reduced first-dose infusion reactions compared to clinical trials.
The product is generally viewed as more tolerable than other IV options.
Beyond infusion time and cost, what drives IV share?
What SC dosing advantage will BRIUMVI offer?
Why prioritize progressive MS for azer-cel?
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Next TG Therapeutics earnings date
Q3 20253 Nov, 2025
Next TG Therapeutics earnings date
Q3 20253 Nov, 2025
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Frequently asked questions
TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell malignancies and autoimmune diseases. The company's therapeutic product candidates include Ublituximab, an investigational glycoengineered monoclonal antibody for the treatment of B-cell non-hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), and relapsing forms of multiple sclerosis; Umbralisib, an oral inhibitor of PI3K delta and CK1 epsilon for the treatment of CLL and follicular lymphoma; Cosibelimab, a human monoclonal antibody that binds to programmed death ligand 1 (PD-L1) and blocks its interactions with PD-1 and B7.1 receptors; TG-1701 is an orally available Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK over ibrutinib in in vitro kinase screening; TG-1801, a bispecific CD47/CD19 antibody generated by fusion technology platform across two distinct proteins each comprising single chain moieties from humanized IgG.
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