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TG Therapeutics (TGTX) investor relations material
TG Therapeutics H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Market landscape and product differentiation
Relapsing MS affects nearly a million in the US, with 300,000–400,000 treated and 80,000 seeking new therapies annually.
About half of new MS patients start on anti-CD20 monoclonal antibodies, with three main drugs in the class.
Differentiation in the IV segment includes a one-hour infusion time versus competitors’ 2–3.5 hours and a 20–25% lower cost.
Majority of patients (65%) choose IV over subcutaneous options, with a subcutaneous formulation in development.
Commercial performance and growth strategy
2025 revenue guidance raised to $570–$575 million, based on new patient starts and therapy persistence.
Market share in the IV segment has grown from 25% to nearly one-third.
Most new patients are switches from other therapies, with switchers outnumbering newly diagnosed cases.
Direct-to-patient marketing, including TV campaigns, was recently launched to boost awareness.
Clinical experience and patient outcomes
Real-world data shows strong efficacy and improved tolerability, especially lower infusion reaction rates after the first dose.
Use of Tylenol in practice has reduced first-dose infusion reactions compared to clinical trials.
The product is generally viewed as more tolerable than other IV options.
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