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TransCode Therapeutics (RNAZ) investor relations material
TransCode Therapeutics Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary14 Nov, 2025
Executive summary
Completed acquisition of ABCJ, LLC and its subsidiary Polynoma, expanding the pipeline with seviprotimut-L, a Phase 3-ready melanoma vaccine candidate.
Secured $25 million in new capital through a private placement, with $20 million in cash and $5 million via a promissory note, extending cash runway into Q4 2026.
Appointed Philippe Calais as CEO and Elizabeth Czerepak as an independent director, strengthening leadership.
Financial highlights
Net loss of $21.2 million for the nine months ended September 30, 2025, compared to $10.8 million in the prior year period.
Operating expenses rose to $12.0 million for the nine months, up from $10.6 million year-over-year, driven by increased R&D and clinical trial costs.
Cash balance at September 30, 2025, was $2.8 million, prior to the October investment.
Accumulated deficit reached $84.4 million.
Outlook and guidance
Cash and new investment expected to fund operations into Q4 2026.
Plans to initiate a Phase 2a clinical trial for TTX-MC138 in the first half of 2026.
Ongoing focus on advancing both TTX-MC138 and seviprotimut-L programs.
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Next TransCode Therapeutics earnings date
Q4 202515 Apr, 2026
Next TransCode Therapeutics earnings date
Q4 202515 Apr, 2026
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Frequently asked questions
TransCode Therapeutics Inc. is a U.S.-based biotechnology company focused on developing RNA-targeted therapies for treating cancer. The company uses its proprietary TTX platform to design and deliver RNA-based therapeutics aimed at addressing previously undruggable cancer targets. TransCode’s research primarily involves preclinical and clinical development of treatments for metastatic and solid tumors, aiming to improve precision and efficacy in cancer treatment. The company is headquartered in Boston, Massachusetts, and its shares are listed on the NASDAQ.
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