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Transgene (TNG) investor relations material
Transgene Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary4 Nov, 2025
Executive summary
Presented new immunogenicity data for TG4050, an individualized neoantigen vaccine, showing robust CD8+ T-cell responses and potential to reduce relapse risk in head and neck cancer patients.
Updated positive clinical results for BT-001, an oncolytic virus, demonstrating antitumoral activity in advanced refractory tumors.
Ongoing expansion of the myvacⓇ platform with plans for a new Phase I trial in a second solid tumor indication.
Financial highlights
Research Tax Credit increased to €5.8 million in Q3 2025 from €4.8 million in Q3 2024, reflecting clinical trial progress.
Operating income for Q3 2025 was €6.13 million, up from €5.0 million in Q3 2024.
Cash position as of September 30, 2025, was €12.8 million, down from €16.7 million at year-end 2024.
Net cash burn for the first nine months of 2025 was €28.8 million, compared to €31.3 million in the same period of 2024.
Outlook and guidance
Completion of Phase II randomization for TG4050 in operable HNSCC expected by early 2026, with first immunogenicity data in H2 2026.
First efficacy data (2-year DFS) anticipated once all patients reach two-year follow-up or event.
Business funded until end of December 2026, supported by a €48 million credit facility.
TG4050 accelerated regulatory pathway details
Second myvac® indication trial initiation timeline
Cash burn rate vs. 2026 funding projection
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Status Update14 Nov, 2025
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Frequently asked questions
Transgene SA is a biotechnology company focused on developing innovative immunotherapies for cancer treatment. The company's core expertise lies in the design and development of therapeutic vaccines and oncolytic viruses. Transgene leverages advanced viral vector technology to create targeted treatments that aim to induce immune responses against cancer cells, either by directly attacking them or by enhancing the body's immune system to do so. Key products in its clinical-stage pipeline include TG4050, an individualized therapeutic vaccine developed using the myvac platform, and TG4001, aimed at treating HPV-positive cancers. The company also develops oncolytic viruses like BT-001 and TG6050 under its Invir.IO platform. The company is headquartered in Illkirch-Graffenstaden, France, and its shares are listed on the Euronext Paris.
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