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Travere Therapeutics (TVTX) investor relations material
Travere Therapeutics Jefferies London Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Jefferies London Healthcare Conference 2025 summary18 Nov, 2025
Company overview and pipeline highlights
Focuses on rare kidney diseases, with commercial and late-stage development activities.
FILSPARI is approved in the US, Europe, and UK for IgA nephropathy and has a pending PDUFA date for FSGS in January.
Pegtibatinase is in phase III for classical homocystinuria, with plans to restart enrollment in 2025.
Leadership expects to be first to market for FSGS therapy.
Regulatory and clinical development updates
FDA review for FSGS SNDA is on track, with no major changes in review team or process.
Advisory committee meeting for FSGS was canceled, indicating a smooth review process.
Draft labeling discussions are expected about a month before the PDUFA date.
Requested a broad label for FSGS, covering all subtypes and patients eight years and older.
Post-marketing requirements are possible but none anticipated at this stage.
Clinical data and market positioning
Phase III DUPLEX trial showed consistent proteinuria reduction but missed statistical significance on eGFR.
Post-hoc analyses and external datasets support a strong correlation between deep proteinuria reduction and lower kidney failure risk.
FILSPARI is positioned as foundational therapy, with potential for combination use as new biologics emerge.
High compliance and persistence rates observed, especially in patients with lower proteinuria.
FSGS label: broad vs. restricted market impact
FILSPARI strategy vs. emerging biologics
HCU Phase 3 restart and study design details
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Next Travere Therapeutics earnings date
Evercore ISI 8th Annual HealthCONx Conference2 Dec, 2025
Next Travere Therapeutics earnings date
Evercore ISI 8th Annual HealthCONx Conference2 Dec, 2025
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Leroy DaleyApp Store
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Eferix Drawings Google Play
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Frequently asked questions
Travere Therapeutics Inc is a biopharmaceutical company focused on developing and commercializing therapies for rare diseases. The company’s research and commercial efforts target conditions related to nephrology, hepatology, and metabolic disorders. It serves patients through both approved treatments and investigational programs. The company is headquartered in San Diego, California, and its shares are listed on the NASDAQ.
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