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UroGen Pharma (URGN) investor relations material

UroGen Pharma Piper Sandler 37th Annual Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Piper Sandler 37th Annual Healthcare Conference summary2 Dec, 2025

Company overview and technology

  • Focuses on addressing unmet needs in urothelial cancers by delivering local medicine using RTGel, a reverse thermal gel that transitions from liquid to gel at body temperature, enabling prolonged drug exposure.

  • Recently received approval for a second drug targeting low-grade, intermediate-risk non-muscle-invasive bladder cancer (NMIBC), expanding from its initial rare disease indication.

Product launch and commercialization dynamics

  • ZUSDURI is the first FDA-approved non-surgical option for intermediate-risk NMIBC, addressing recurrence and reducing the need for repeated surgeries in elderly patients.

  • Commercialization is complex due to the procedure-based nature of the drug, requiring operational support, reimbursement education, and nurse training.

  • The main challenge is the lag between patient identification and dosing, currently averaging 60 days, with efforts underway to reduce this to 15-20 days as seen with JELMYTO.

Reimbursement and revenue recognition

  • Revenue is recognized upon shipment of each dose, with a just-in-time inventory model and weekly shipments for each patient.

  • Reimbursement currently takes 45-60 days under a miscellaneous J-code, but a permanent J-code effective January 1 will streamline the process and boost physician confidence.

  • A service warranty is offered to support reimbursement, with positive trends observed so far.

Shorten ZUSDURI 60-day dosing lag
Risks of UGN-102 to UGN-103 product switch
ZUSDURI's differentiation from new competitors
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Q4 202513 Mar, 2026
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Frequently asked questions

UroGen Pharma Ltd. is a biotechnology company focused on developing and commercializing innovative treatments for urothelial and specialty cancers. The company utilizes its proprietary RTGel technology, a reverse-thermal hydrogel that enhances the therapeutic profiles of existing drugs by providing longer exposure to the urinary tract tissue, making local therapy more effective. The company is headquartered in Princeton, NJ, with operations in Israel, and its shares are listed on the Nasdaq.

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