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Ventyx Biosciences (VTYX) investor relations material
Ventyx Biosciences Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Focused on developing oral therapies for autoimmune, inflammatory, and neurodegenerative diseases, with clinical-stage candidates VTX2735, VTX3232, tamuzimod, and VTX958 in various trials and stages of development.
Achieved key milestones with positive Phase 2a data for VTX3232 in Parkinson's disease and Phase 2 data in obesity/cardiovascular risk factors.
VTX3232 demonstrated significant reductions in inflammatory biomarkers, supporting its potential as a next-generation oral anti-inflammatory therapy.
Net loss for Q3 2025 was $22.8 million, and $77.3 million for the nine months ended September 30, 2025, reflecting ongoing R&D investment and no product revenue.
Raised $95.0 million in a March 2024 private placement and $26.6 million in a September 2024 Series A preferred stock private placement.
Financial highlights
Cash, cash equivalents, and marketable securities totaled $192.6 million as of September 30, 2025, expected to fund operations into at least H2 2026.
Q3 2025 net loss was $22.8 million, improved from $35.2 million in Q3 2024; nine-month net loss was $77.3 million, improved from $105.8 million in the prior year period.
Operating expenses for Q3 2025 were $24.9 million, down from $38.6 million in Q3 2024, driven by lower R&D and G&A costs.
R&D expenses were $17.7 million and G&A expenses were $7.2 million for Q3 2025.
Basic and diluted net loss per share was $0.32 for Q3 2025 and $1.08 for the nine months ended September 30, 2025.
Outlook and guidance
Existing cash, cash equivalents, and marketable securities expected to fund obligations for at least 12 months from the report date and into at least the second half of 2026.
Anticipates increased R&D costs for VTX2735 and decreased costs for tamuzimod and VTX958 as trials close out.
Topline data from the Phase 2 study of VTX2735 in recurrent pericarditis expected in Q4 2025.
Exploring partnership opportunities for tamuzimod in ulcerative colitis and VTX958 in Crohn's disease.
No product revenue expected for several years; future funding needs anticipated for continued development and potential commercialization.
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