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Veradermics (MANE) investor relations material
Veradermics Corporate presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Market opportunity and unmet need
Pattern hair loss (PHL) affects about 80 million Americans, with a projected $30B commercial opportunity by 2028, making it the most prevalent chronic dermatological condition in the US.
Current treatments are fragmented, with high dissatisfaction, poor adherence, and no FDA-approved oral options for women.
Women represent a significant untapped market, showing higher willingness to treat and greater impact on quality of life.
Only 9% of patients are satisfied with current treatments, and 46% are actively seeking new options.
Recent increases in low-dose oral minoxidil prescriptions highlight pent-up demand.
Product profile and clinical differentiation
VDPHL01 is an extended-release oral minoxidil tablet designed to optimize hair growth efficacy and cardiac safety.
Demonstrates fast onset (visible results in 2 months), consistent response (>90% PRO at 4 months), and intense effect (47.3 non-vellus hairs/cm² increase).
Phase 2 data show superior efficacy and visible improvement compared to topical and immediate-release oral minoxidil.
Generally well-tolerated with no treatment-related serious cardiac or hormonal adverse events to date.
First potential FDA-approved oral product for PHL in both men and women.
Clinical development and regulatory status
Three registration-directed trials are ongoing: two in males (Phase 2/3 and confirmatory Phase 3) and one in females (Phase 2/3), with topline readouts expected in 2026.
Phase 2 open-label study in 43 subjects (21 males, 22 females) demonstrated proof of concept for safety and efficacy.
Blinded expert review confirmed superior improvement and higher rates of moderate/great improvement versus comparators.
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