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Verastem
Verastem (VSTM) investor relations material
Verastem Guggenheim Securities Emerging Outlook: Biotech Summit 2026 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Guggenheim Securities Emerging Outlook: Biotech Summit 2026 summary11 Feb, 2026
Commercial performance and market uptake
Achieved over 50% sales growth from Q2 to Q4, beating analyst consensus for three consecutive quarters.
Drug adoption is broad, with strong uptake in both major academic centers and large community practices.
Average patient duration on therapy is 18 months, supporting a recurring revenue model.
Reimbursement is robust for both on-label and off-label use, including KRAS wild type cases.
A new promotional campaign is launching to position the therapy as the preferred post-frontline option.
Clinical development and trial updates
Confirmatory trial (RAMP 301) completed accrual, with a final readout expected around mid-next year.
Trial size increased from 270 to 300 patients to maintain statistical power, with positive interim feedback.
Japanese bridging study confirmed efficacy across all patient types, supporting conditional approval in Japan.
RAMP 205 in pancreatic cancer showed an 83% response rate with full-dose chemo, with expanded cohort data due mid-year.
G12D inhibitor (VS-7375) demonstrated 58% response in pancreatic and 69% in lung cancer, with U.S. trials showing improved tolerability.
Strategic outlook and future plans
Awaiting potential NCCN guideline inclusion, which could further boost growth.
RAMP 301 could expand the addressable U.S. market to 6,000–10,000 patients if wild type is included.
U.S. phase I study of VS-7375 is progressing, with single-agent and combination arms in multiple cancers.
Plans to pursue both single-agent and combination strategies in front-line lung and pancreatic cancers.
Company-sponsored events will provide key data updates on pipeline progress throughout the year.
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Next Verastem earnings date
Q4 202517 Mar, 2026
Verastem
Next Verastem earnings date
Q4 202517 Mar, 2026
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Frequently asked questions
Verastem Inc is a development-stage biopharmaceutical company primarily focused on the development and commercialization of new medicines aimed at improving the lives of patients diagnosed with cancer. The company is engaged in advancing a pipeline of novel small-molecule drugs that target critical signaling pathways involved in cancer cell survival and tumor growth. These pathways include RAF/MEK inhibition and focal adhesion kinase (FAK) inhibition, which are central to the company's research and development efforts. The company is headquartered in Needham, Massachusetts, and its shares are listed on the Nasdaq.
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