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Vicore Pharma (VICO) investor relations material

Vicore Pharma Morgan Stanley 23rd Annual Global Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Morgan Stanley 23rd Annual Global Healthcare Conference summary8 Sep, 2025

Company overview and scientific focus

  • Focuses on the angiotensin II pathway, specifically targeting the AT2 receptor for fibrotic and inflammatory diseases.

  • Lead indication is idiopathic pulmonary fibrosis (IPF), a disease with high unmet need and significant commercial potential.

  • Lead compound has completed phase I and IIA trials, with a large phase IIB trial ongoing.

Mechanism of action and differentiation

  • AT2 receptor activation promotes anti-fibrotic, anti-inflammatory, and vasodilatory effects, supporting tissue repair.

  • Approach aims to regenerate lung tissue by stimulating alveolar epithelial type II cells, addressing both fibrosis and vascular dysfunction.

  • Differentiates from existing therapies by targeting epithelial repair and vascular components, not just fibrotic buildup.

Market landscape and treatment challenges

  • Only two approved IPF drugs exist, both with poor tolerability and limited efficacy, leading to low treatment rates and short duration on therapy.

  • IPF market is valued at $4 billion and expected to grow, with significant opportunity for better-tolerated, more effective treatments.

  • Recent phase III successes set a new efficacy bar, but more therapies and combination approaches are needed.

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Vicore Pharma Holding, a clinical-stage biopharmaceutical company, develops pharmaceutical products for the treatment of orphan lung diseases.

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