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Voyager Therapeutics (VYGR) investor relations material
Voyager Therapeutics Baird Global Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Baird Global Healthcare Conference 2025 summary9 Sep, 2025
Company overview and strategy
Aspires to be a multimodality neurotherapeutics company, expanding beyond gene therapy to leverage neurogenetics and multiple delivery approaches.
Focuses on Alzheimer's disease with several programs and maintains a strong partnership model to access external expertise and non-dilutive funding.
Maintains a robust cash position of $262 million, providing runway into 2028, with additional milestone payments expected.
NeuroShuttle and ALPL program updates
NeuroShuttle platform leverages TRACER™ AAV capsid discovery to develop shuttles that cross the blood-brain barrier using specific receptors.
ALPL shuttle shows distinct pharmacokinetics and safety profile compared to transferrin receptor shuttles, with prolonged brain presence and no observed anemia.
Plans to announce specific ALPL research programs within the next six months.
Open to partnerships for NeuroShuttle, aiming to replicate past success in non-dilutive deals and access external chemistry expertise.
Alzheimer's pipeline and Tau programs
Pipeline includes two Tau-targeted programs: a pathologic-specific C-terminal Tau antibody in a multiple ascending dose study, and a TRACER™ AAV gene therapy for Tau knockdown.
Tau antibody program expects biomarker and Tau-PET readout in the second half of 2026, with external catalysts from Johnson & Johnson and Biogen data.
Gene therapy program shows promising non-human primate data with effective knockdown at lower doses and reduced liver targeting; clinical entry planned for next year.
APOE program aims to decrease E4 and increase E2 to address high-risk Alzheimer's populations, with gene therapy showing efficacy in animal models.
ALPL shuttle: What specific diseases will it target?
Tau antibody vs. gene therapy: patient population?
Timing for Alzheimer's program partnerships?
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Next Voyager Therapeutics earnings date
Q3 20256 Nov, 2025
Next Voyager Therapeutics earnings date
Q3 20256 Nov, 2025
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Frequently asked questions
Voyager Therapeutics Inc. is a biotechnology company focused on developing gene therapies for the treatment of severe neurological diseases. The company leverages its proprietary platform to create therapies designed to deliver genetic material directly to targeted cells in the brain and other parts of the nervous system. Voyager's research and development efforts focus on treating conditions such as Parkinson’s disease, Huntington’s disease, and other central nervous system disorders. The company is headquartered in Cambridge, Massachusetts, and its shares are listed on the NASDAQ.
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