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Xencor (XNCR) investor relations material
Xencor Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Q3 revenue was $116.5M and net income was $39.4M, with diluted EPS of $0.50; results included $77.4M of one-time Alexion settlement revenue recognized as royalties.
Pipeline advanced: XmAb819 dose selection supported proposed Phase 3 planning, XmAb412 began enrolling in Phase 1, and a XmAb541/XmAb808 combination trial was initiated.
Financial highlights
Q3 revenue was $116.5M vs. $21.0M a year earlier, including $87.5M of royalties and $29.0M of milestones; 9M revenue was $172.3M vs. $97.3M.
Q3 operating income was $22.9M vs. a $47.5M loss; net income was $39.4M vs. a $6.0M loss, with diluted EPS of $0.50 vs. $(0.08).
9M operating loss was $92.1M vs. $123.9M; net loss was $111.2M vs. $85.3M.
Q3 R&D expense rose to $84.3M from $54.4M, partly offset by lower stock compensation; G&A fell to $9.4M from $14.2M, primarily from a non-recurring legal expense recovery.
Q3 other income, net, was $16.4M vs. $41.5M, primarily reflecting lower unrealized equity-security gains; 9M R&D was $220.9M vs. $174.6M and G&A was $43.5M vs. $46.6M.
Outlook and guidance
Year-end 2026 cash, cash equivalents and marketable debt securities are expected at $480M–$500M; current resources are expected to support operations into 2029, subject to assumptions and potential milestone payments.
XmAb819 FDA engagement on a potential accelerated pathway is planned for 1H27; subject to feedback, a global randomized Phase 3 study may begin by year-end 2027.
XmAb942 blinded interim analysis is expected around year-end 2026, with its Phase 2b primary endpoint analysis targeted for 2H27.
Initial XmAb412 data and additional XmAb819 IV and subcutaneous cohort results are planned for 1H27.
- XmAb819’s 400 µg/kg dose showed 45.5% ORR and 82% 6-month PFS.XNCR
Study update - Lead XmAb®-engineered antibodies advance toward pivotal studies in oncology and immunology.XNCR
Corporate presentation - Late-stage T-cell engager and immunology programs advance, with pivotal data expected soon.XNCR
12th Annual Cantor Fitzgerald Global Healthcare Conference - Q2 2026 revenue rose on settlements and milestones; Alexion dispute resolved with $105M payment.XNCR
Q2 2026 - Key clinical updates on bispecific and TL1A programs signal major advances in immunology and oncology.XNCR
Cantor Global Healthcare Conference 2025 - Lead clinical programs show strong efficacy and safety, with pivotal studies planned for 2027.XNCR
Corporate presentation - Accelerating clinical data and innovation in bispecifics drive pipeline and commercial focus.XNCR
Bank of America Global Healthcare Conference 2026 - XmAb942 and XmAb412 advance as next-gen IBD therapies, with pivotal data expected in 2027.XNCR
Digestive Disease Week Conference - XmAb819 achieved 25% response and 70% disease control in advanced ccRCC with good tolerability.XNCR
Study Result
Next Xencor earnings date
Next Xencor earnings date
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