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XORTX Therapeutics (XRTX) investor relations material

XORTX Therapeutics IPO filing summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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IPO filing summary25 Sep, 2025

Company overview and business model

  • Late clinical-stage biotech focused on therapies for diseases linked to purine and uric acid metabolism, targeting gout, autosomal dominant polycystic kidney disease (ADPKD), type 2 diabetic nephropathy (T2DN), and acute kidney injury (AKI) from respiratory virus infection.

  • Pipeline includes XRx-026 (gout), XRx-008 (ADPKD), XRx-101 (AKI), and XRx-225 (T2DN), with proprietary oxypurinol formulations and a pipeline-in-a-product strategy.

  • Lead program XRx-026 for gout is prioritized for near-term NDA filing and potential revenue generation; XRx-008 is in late-stage development for ADPKD.

  • Holds exclusive patents in the US and Europe for uric acid lowering agents in diabetic nephropathy and other indications.

Financial performance and metrics

  • As of June 30, 2025, pro forma as adjusted cash position is $5.9 million, with total capitalization of $7.9 million after the offering.

  • Net tangible book value per share post-offering is estimated at $0.69, with immediate dilution of $0.11 per share to new investors at the assumed offering price.

  • Company has incurred operating losses and negative cash flow for fiscal years 2023 and 2024.

Use of proceeds and capital allocation

  • Estimated net proceeds of $3.8 million (assuming no pre-funded warrants exercised) will fund ongoing R&D, working capital, and general corporate purposes.

  • Management retains broad discretion over allocation of proceeds, with a substantial portion expected for working capital.

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Q3 202514 Nov, 2025
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Frequently asked questions

XORTX Therapeutics Inc is a Canada-based clinical-stage biopharmaceutical company focused on developing therapies for chronic kidney disease and other health conditions related to abnormal purine metabolism and uric acid imbalance. The company’s lead drug candidates aim to lower serum uric acid levels to prevent or slow the progression of kidney and cardiovascular diseases. XORTX conducts research and clinical trials to advance its proprietary formulations. The company is headquartered in Calgary, Alberta, and its shares are listed on the NASDAQ.

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