Alpha Cognition (ACOG) Fireside Chat summary

Introduction and agenda

• Fireside chat format with pre-set questions and open Q&A for investors, focusing on commercial adoption and clinical development.

Current industry trends

• Long-term care market for Alzheimer's is valued at $2.2 billion, with 15,000 nursing homes in the US, 5,000 specializing in Alzheimer's.

• Most patients are switched from generics like Aricept due to side effects and loss of efficacy, with ZUNVEYL positioned as a better-tolerated alternative.

Challenges and overcoming obstacles

• Inventory build remains choppy due to rapid growth and distributor adjustments, expected to normalize in two quarters.

• Payer coverage is expanding gradually, with critical mass expected after three PBM contracts by 2026.

• Adherence in nursing homes is high, but tolerability and polypharmacy remain key challenges.