Ceryvyn Therapeutics (CYV) H2 2026 earnings summary
Event summary combining transcript, slides, and related documents.
H2 2026 earnings summary
6 Sep, 2026Executive summary
Achieved a significant turnaround with a profit of A$330.4 million for FY26, compared to a loss of A$251.1 million in FY25, primarily due to a one-time gain from the derecognition of the Development Funding Agreement (DFA).
Settled the DFA, removing a substantial liability and restoring solvency, enabling a strategic reset and focus on rare disease drug development.
Redirected lead asset CYV-101 to target lymphangioleiomyomatosis (LAM), a rare lung disease, leveraging existing scientific and manufacturing investments.
Resumed trading on the ASX in June 2026 and rebranded to reflect the new strategic direction.
Financial highlights
FY26 profit after tax: A$330.4 million (FY25: loss of A$251.1 million), driven by a A$357.1 million gain on DFA derecognition.
Revenue: A$1,000 (FY25: A$39,000), with other income of A$189,000.
Research and development expenses: A$2.2 million (FY25: A$193.8 million); administrative expenses: A$9.7 million (FY25: A$48.2 million).
Net tangible assets per share: 2.16 cents (FY25: -24.93 cents).
Cash and cash equivalents at year-end: A$30.0 million (FY25: A$73.9 million).
No dividends declared or paid for FY26 or FY25.
Outlook and guidance
Sufficient cash reserves to fund the planned three-stage LAM development program through initial proof-of-concept studies.
Focused on disciplined capital allocation, with progression dependent on scientific data quality at each milestone.
No specific financial guidance provided due to the early stage of the LAM program and inherent uncertainties.
Latest events from Ceryvyn Therapeutics
- Repurposing OPT-302 for LAM targets a rare disease market with high unmet need and strong commercial logic.CYV
Corporate presentation - OPT-302 targets LAM with a capital-efficient, stage-gated rare disease strategy and strong leadership.CYV
Investor presentation - Advancing OPT-302 for LAM with robust funding, expert leadership, and a focused rare disease strategy.CYV
Investor update - Cash reserves at AUD $31.2M, LAM program underway, ASX reinstatement targeted in H1 2026.CYV
Q3 2026 TU - Phase 3 wet AMD trials fully enrolled; cash runway extended through 2025 topline data.CYV
H2 2024 - Profit surges on DFA settlement as focus shifts to LAM, with cash reserves funding near-term plans.CYV
H1 2026 - Sozinibercept shows superior efficacy in wet AMD and nears pivotal phase III results in 2025.CYV
H.C. Wainwright 4th Annual Ophthalmology Virtual Conference - Sozinibercept aims to set a new standard in wet AMD by improving vision outcomes as an add-on therapy.CYV
Jefferies 2024 Global Healthcare Conference - Net loss reached US$131.9M as cash runway supports pivotal trials amid funding uncertainty.CYV
H1 2025