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Ceryvyn Therapeutics (CYV) investor relations material
Ceryvyn Therapeutics Q1 2027 TU earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
CYV-101 Stage 1 LAM preclinical biology and inhalation work continued; nebulisation feasibility and preliminary animal safety and tolerability studies remain on track.
Planned clinical development advanced through a Polarian Xe-MRI agreement, Stage 2 CRO selection after quarter-end, patient engagement planning and the inaugural Scientific Advisory Board meeting.
Financial highlights
Cash and equivalents were AUD $27.463m at 30 September 2026, down from AUD $30.021m at 30 June 2026; operating cash outflow was AUD $2.364m.
Operating cash outflow increased from AUD $1.1m in the previous quarter; interest income was AUD $0.3m.
Cash flow included a negative AUD $194k foreign-exchange movement; quarter-end cash comprised AUD $3.915m in bank balances and AUD $23.548m in call deposits.
Outlook and guidance
Stage 1 preclinical biology and inhalation studies are underway; progression between the three development stages depends on predefined scientific, operational and capital allocation criteria reviewed by the Board.
The selected Australian-based CRO is expected to support Stage 2 protocol development, ethics submissions, site feasibility, nebulised dosing materials, safety monitoring and data services; scope and budget will be refined as study requirements are confirmed.
- Repurposing OPT-302 for LAM targets a rare disease market with high unmet need and strong commercial logic.CYV
Corporate presentation - OPT-302 targets LAM with a capital-efficient, stage-gated rare disease strategy and strong leadership.CYV
Investor presentation - Returned to profitability with A$330.4 million profit after DFA settlement and strategic reset.CYV
H2 2026 - Advancing OPT-302 for LAM with robust funding, expert leadership, and a focused rare disease strategy.CYV
Investor update - Cash reserves at AUD $31.2M, LAM program underway, ASX reinstatement targeted in H1 2026.CYV
Q3 2026 TU - Phase 3 wet AMD trials fully enrolled; cash runway extended through 2025 topline data.CYV
H2 2024 - Profit surges on DFA settlement as focus shifts to LAM, with cash reserves funding near-term plans.CYV
H1 2026 - Sozinibercept shows superior efficacy in wet AMD and nears pivotal phase III results in 2025.CYV
H.C. Wainwright 4th Annual Ophthalmology Virtual Conference - Net loss reached US$131.9M as cash runway supports pivotal trials amid funding uncertainty.CYV
H1 2025
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