Cryoport (CYRX) Q1 2025 earnings summary
Event summary combining transcript, slides, and related documents.
Q1 2025 earnings summary
14 Mar, 2026Executive summary
Q1 2025 revenue from continuing operations reached $41.0 million, up 10% year-over-year, driven by strong growth in Life Sciences Services and commercial Cell & Gene therapy revenue, which rose 33% year-over-year.
Supported 711 global clinical trials as of March 31, 2025, a net increase of 36 trials year-over-year, and 20 commercial therapies, with 79 trials in Phase 3.
Announced a strategic partnership with DHL, including the divestiture of CRYOPDP for $195 million, expected to close in Q2 or Q3 2025, to enhance global reach and provide a capital infusion.
Launched new products such as the MVE High-Efficiency 800C cryogenic storage system, expanding the product portfolio.
Financial highlights
Life Sciences Services revenue rose 17% year-over-year to $22.9 million; BioStorage/BioServices revenue increased 23% to $4.3 million; Life Sciences Products revenue grew 2% to $18.2 million.
Gross margin improved to 45.4% from 40.4% year-over-year, with Life Sciences Services gross margin at 47.9% and Products at 42.3%.
Net loss for Q1 2025 was $12.0 million, improved from $18.9 million in Q1 2024; net loss per share was $0.28 versus $0.43.
Adjusted EBITDA loss improved to $2.8 million from $6.7 million year-over-year.
Cash, cash equivalents, and short-term investments totaled $244.0 million as of March 31, 2025.
Outlook and guidance
Full-year 2025 revenue guidance is $165.0–$172.0 million, representing 5%–10% organic growth year-over-year.
Anticipates a return to positive adjusted EBITDA during 2025, with further margin improvements expected in 2026 and 2027.
Expects minimal impact from tariffs, with related charges anticipated to be passed through if incurred.
Ongoing softness in product sales anticipated, but continued growth in services business.
Up to 17 additional therapy approval filings and several label/geographic expansions anticipated in 2025.
Latest events from Cryoport
- Q3 2024 saw service growth, margin gains, and reaffirmed guidance despite product softness.CYRX
Q3 202414 Mar 2026 - Q2 2024 revenue hit $57.6M, with 51% cell/gene therapy growth and a $63.8M impairment loss.CYRX
Q2 202414 Mar 2026 - 2024 revenue hit $228.4M, Q4 margin rose to 45.8%, and 2025 guidance is $240–$250M with EBITDA positivity.CYRX
Q4 202414 Mar 2026 - FY2025 revenue rose 12% to $176.2M, with margin expansion and strong CGT market leadership.CYRX
Q4 20253 Mar 2026 - DHL acquires CRYOPDP for $195M, boosting growth, margins, and global reach in cell and gene therapy.CYRX
Investor Update26 Dec 2025 - Cost-cutting, innovation, and ESG focus drive growth as shareholders vote on key governance matters.CYRX
Proxy Filing2 Dec 2025 - Virtual annual meeting to vote on directors, auditor, and executive pay June 6, 2025.CYRX
Proxy Filing2 Dec 2025 - Q2 2025 revenue up 14–14.5%, net income surged on CRYOPDP sale, guidance reaffirmed.CYRX
Q2 202523 Nov 2025 - Q3 revenue up 15.4% year-over-year, gross margin at 48.2%, guidance raised to $170–$174M.CYRX
Q3 202513 Nov 2025