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OptiNose (OPTN) Q4 2024 earnings summary

Event summary combining transcript, slides, and related documents.

Logotype for OptiNose Inc

Q4 2024 earnings summary

5 Jun, 2025

Executive summary

  • XHANCE net revenue reached $22.4 million in Q4 2024 and $78.2 million for the full year, up 13% and 10% year-over-year, respectively.

  • Prescription demand inflected upward in September 2024, with Q4 NRx up 12% and TRX up 23% sequentially from Q3 2024.

  • Achieved first-ever positive income from operations in Q4 2024 at $0.4 million.

Financial highlights

  • Q4 2024 net revenue: $22.4 million (up 13% year-over-year); full year 2024: $78.2 million (up 10%).

  • Q4 2024 net loss: $0.4 million ($0.04/share); full year 2024 net loss: $21.5 million ($2.12/share), both improved from prior year.

  • Cash and cash equivalents at year-end: $84.5 million.

  • SG&A plus R&D expenses for 2024: $87.3 million, up from $85.1 million in 2023.

  • Weighted average shares outstanding for 2024: 10.2 million.

Segment performance

  • XHANCE prescriptions showed strong growth: NRx up 12% and TRX up 23% sequentially from Q3 to Q4 2024.

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