Pfizer (PFE) Q1 2023 earnings summary
Event summary combining transcript, slides, and related documents.
Q1 2023 earnings summary
6 Nov, 2026Executive summary
Q1 was described as a solid, foundational quarter, with results in line with expectations; non-COVID revenue grew 5% operationally YoY while total revenue declined 26% operationally.
Comirnaty and Paxlovid generated $7.1 billion in combined Q1 revenue; more than 250 million patients were treated with medicines and vaccines during the quarter.
Financial highlights
Reported diluted EPS fell 29% to $0.97; Adjusted diluted EPS declined 20% operationally to $1.23.
FX reduced Q1 revenue by $730 million, or 3%, and Adjusted diluted EPS by $0.07, or 4%, versus the prior-year quarter.
Strong Paxlovid sales partially offset the expected Comirnaty decline; increased selling, information and administration investment supported anticipated launches.
Outlook and guidance
FY 2023 revenue guidance remains $67 billion–$71 billion, implying a 31% operational decline at the midpoint; Adjusted diluted EPS guidance remains $3.25–$3.45.
Non-COVID revenue guidance remains 7%–9% operational growth; launches concentrated in Q3 and Q4 are expected to drive faster growth in H2 than H1.
COVID product sales are expected to be significantly lower in Q2 than Q1; more substantial vaccine deliveries are expected from September, while Paxlovid is expected to shift to a commercial market in H2.
FY 2023 FX is expected to reduce Adjusted diluted EPS by $0.13 versus FY 2022.
Latest events from Pfizer
- Vaccine-led Q1 growth lifted 2021 guidance while core-business growth remained on track.PFE
Q1 2021 - Vaccine-led growth lifted FY guidance as major pipeline programs advanced.PFE
Q2 2021 - Record 2021 growth underpins $100B midpoint revenue guidance for 2022.PFE
Q4 2021 - Comirnaty lifted Q3 growth and guidance as pipeline and safety risks persisted.PFE
Q3 2021 - Adjusted EPS rose 44% as guidance improved, with pipeline and deals aimed at offsetting future LOEs.PFE
Q3 2022 - COVID products drove 82% operational revenue growth; FY22 revenue outlook held at $98B-$102B.PFE
Q1 2022 - Strong Q2 growth lifted FY22 operational guidance despite FX pressure.PFE
Q2 2022 - Q4 growth and a deep launch pipeline underpin 2023 growth ex-COVID despite lower total revenue.PFE
Q4 2022 - COVID-19 declines drove Q2 revenue down 53%; FY Adjusted EPS guidance held at $3.25-$3.45.PFE
Q2 2023