Pfizer (PFE) Q2 2021 earnings summary
Event summary combining transcript, slides, and related documents.
Q2 2021 earnings summary
6 Nov, 2026Executive summary
Q2 revenue grew 86% operationally, driven by COVID-19 vaccine sales and growth across other key products; revenue excluding vaccine direct sales and alliance revenues rose 10% operationally.
More than 1 billion vaccine doses had shipped since December 2020; full-year 2021 guidance for revenue and Adjusted diluted EPS was raised.
Financial highlights
Q2 reported diluted EPS increased 58% YoY; Adjusted diluted EPS increased 73%.
Adjusted cost of sales reduced gross margin by 19 percentage points YoY, primarily due to the vaccine gross-profit split and royalties.
Adjusted tax rate rose to 16.6%; foreign exchange benefited revenue by 6% and Adjusted diluted EPS by $0.03.
Outlook and guidance
FY2021 revenue guidance: $78.0B–$80.0B, including projected COVID-19 vaccine revenue of ~$33.5B based on contracts signed through mid-July; the latest U.S. dose contract was excluded.
FY2021 Adjusted diluted EPS guidance increased to $3.95–$4.05, or 77% growth at midpoint vs. 2020, including an expected 4% FX benefit.
Excluding the vaccine, FY2021 revenue guidance is $45B–$47B, representing ~7% operational growth at midpoint; Adjusted diluted EPS is $2.55–$2.65, or ~11% operational growth.
Long-term outlook: risk-adjusted revenue CAGR of at least 6% and double-digit bottom-line growth through 2025; projections exclude the vaccine, business development and potential future mRNA programs.
Vaccine manufacturing capacity could reach 3B doses by year-end 2021; ~2.1B doses were contracted for 2021 delivery as of mid-July.
Latest events from Pfizer
- Vaccine-led Q1 growth lifted 2021 guidance while core-business growth remained on track.PFE
Q1 2021 - Record 2021 growth underpins $100B midpoint revenue guidance for 2022.PFE
Q4 2021 - Comirnaty lifted Q3 growth and guidance as pipeline and safety risks persisted.PFE
Q3 2021 - Adjusted EPS rose 44% as guidance improved, with pipeline and deals aimed at offsetting future LOEs.PFE
Q3 2022 - COVID products drove 82% operational revenue growth; FY22 revenue outlook held at $98B-$102B.PFE
Q1 2022 - Strong Q2 growth lifted FY22 operational guidance despite FX pressure.PFE
Q2 2022 - Q4 growth and a deep launch pipeline underpin 2023 growth ex-COVID despite lower total revenue.PFE
Q4 2022 - Non-COVID growth and a busy H2 launch slate underpin reaffirmed 2023 guidance.PFE
Q1 2023 - COVID-19 declines drove Q2 revenue down 53%; FY Adjusted EPS guidance held at $3.25-$3.45.PFE
Q2 2023